Cardiac dysfunction in beta-thalassemic children.

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dc.contributor.authorChotivittayatarakorn, Pen_US
dc.contributor.authorSeksarn, Pen_US
dc.contributor.authorPathmanand, Cen_US
dc.contributor.authorThisyakorn, Cen_US
dc.contributor.authorSueblinvong, Ven_US
dc.date.accessioned2009-05-27T21:47:44Z
dc.date.available2009-05-27T21:47:44Z
dc.date.issued1993-11-01en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractThe biventricular systolic function was evaluated by M mode and Doppler echocardiography in 16 patients with homozygous beta-thalassemia and beta-thalassemia Hb E disease, aged 5-14 yrs (9.9 +/- 2.4 yr). The left ventricular end-diastolic dimension and left ventricular mass were increased in 88 per cent of the patients. Left ventricular fractional shortening and cardiac index were normal in all but one patient. Fifteen patients had evidence of pulmonary artery hypertension manifested by abnormality in the ratio of right ventricular acceleration time to ejection time (AT/ET). There was good correlation between platelets count and AT/ET (r = -0.70, P = 0.002). Thrombocytosis was noted in 4 patients. Our findings indicated that in beta-thalassemic children, right ventricular dysfunction was detected earlier than left ventricular dysfunction and platelets may play a role in the pathogenesis of pulmonary artery hypertension.en_US
dc.description.affiliationDepartment of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.en_US
dc.identifier.citationChotivittayatarakorn P, Seksarn P, Pathmanand C, Thisyakorn C, Sueblinvong V. Cardiac dysfunction in beta-thalassemic children. Journal of the Medical Association of Thailand. 1993 Nov; 76(11): 591-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/45416
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshEchocardiographyen_US
dc.subject.meshHumansen_US
dc.subject.meshVentricular Dysfunction --complicationsen_US
dc.subject.meshbeta-Thalassemia --complicationsen_US
dc.titleCardiac dysfunction in beta-thalassemic children.en_US
dc.typeJournal Articleen_US
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