Mekong malaria. II. Update of malaria, multi-drug resistance and economic development in the Mekong region of Southeast Asia.

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dc.contributor.authorSocheat, Doungen_US
dc.contributor.authorDenis, Mey Bouthen_US
dc.contributor.authorFandeur, Thierryen_US
dc.contributor.authorZhang, Zaixingen_US
dc.contributor.authorYang, Henglinen_US
dc.contributor.authorXu, Jianweien_US
dc.contributor.authorZhou, Xingwuen_US
dc.contributor.authorPhompida, Samlaneen_US
dc.contributor.authorPhetsouvanh, Rattanaxayen_US
dc.contributor.authorLwin, Sawen_US
dc.contributor.authorLin, Khinen_US
dc.contributor.authorWin, Thanen_US
dc.contributor.authorThan, Soe Winen_US
dc.contributor.authorHtut, Yeen_US
dc.contributor.authorPrajakwong, Somsaken_US
dc.contributor.authorRojanawatsirivet, Chaipornen_US
dc.contributor.authorTipmontree, Rungraweeen_US
dc.contributor.authorVijaykadga, Saowaniten_US
dc.contributor.authorKonchom, Supawadeeen_US
dc.contributor.authorCong, Le Dinhen_US
dc.contributor.authorThien, Nong Thien_US
dc.contributor.authorThuan, Le Khanhen_US
dc.contributor.authorRingwald, Pascalen_US
dc.contributor.authorSchapira, Allanen_US
dc.contributor.authorChristophel, Evaen_US
dc.contributor.authorPalmer, Kevinen_US
dc.contributor.authorArbani, P Ren_US
dc.contributor.authorPrasittisuk, Chusaken_US
dc.contributor.authorRastogi, Ren_US
dc.contributor.authorMonti, Felicianoen_US
dc.contributor.authorUrbani, Carloen_US
dc.contributor.authorTsuyuoka, Reikoen_US
dc.contributor.authorHoyer, Stefanen_US
dc.contributor.authorOtega, Leonarden_US
dc.contributor.authorThimasarn, Krongthongen_US
dc.contributor.authorSongcharoen, Sakdaen_US
dc.contributor.authorMeert, Jean-Pierreen_US
dc.contributor.authorGay, Fredericken_US
dc.contributor.authorCrissman, Lawrenceen_US
dc.contributor.authorCho-Min-Naing,en_US
dc.contributor.authorChansuda, Wongsrichanalaien_US
dc.contributor.authorDarasri, Dowreangen_US
dc.contributor.authorIndaratna, Kaemthongen_US
dc.contributor.authorSinghasivanon, Pratapen_US
dc.contributor.authorChuprapawan, Sirichaien_US
dc.contributor.authorLooareesuwan, Sornchaien_US
dc.contributor.authorSupavej, Suvaneeen_US
dc.contributor.authorKidson, Cheven_US
dc.contributor.authorBaimai, Visuten_US
dc.contributor.authorYimsamran, Suraponen_US
dc.contributor.authorBuchachart, Kasineeen_US
dc.date.accessioned2009-05-27T15:43:49Z
dc.date.available2009-05-27T15:43:49Z
dc.date.issued2003-03-24en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractIn an expansion of the first Mekong Malaria monograph published in 1999, this second monograph updates the malaria database in the countries comprising the Mekong region of Southeast Asia. The update adds another 3 years' information to cover cumulative data from the 6 Mekong countries (Cambodia, China/Yunnan, Lao PDR, Myanmar, Thailand, Viet Nam) for the six-year period 1999-2001. The objective is to generate a more comprehensive regional perspective in what is a global epicenter of drug resistant falciparum malaria, in order to improve malaria control on a regional basis in the context of social and economic change. The further application of geographical information systems (GIS) to the analysis has underscored the overall asymmetry of disease patterns in the region, with increased emphasis on population mobility in disease spread. Of great importance is the continuing expansion of resistance of P. falciparum to antimalarial drugs in common use and the increasing employment of differing drug combinations as a result. The variation in drug policy among the 6 countries still represents a major obstacle to the institution of region-wide restrictions on drug misuse. An important step forward has been the establishment of 36 sentinel sites throughout the 6 countries, with the objective of standardizing the drug monitoring process; while not all sentinel sites are fully operational yet, the initial implementation has already given encouraging results in relation to disease monitoring. Some decreases in malaria mortality have been recorded. The disease patterns delineated by GIS are particularly instructive when focused on inter-country distribution, which is where more local collaborative effort can be made to rationalize resource utilization and policy development. Placing disease data in the context of socio-economic trends within and between countries serves to further identify the needs and the potential for placing emphasis on resource rationalization on a regional basis. Despite the difficulties, the 6-year time frame represented in this monograph gives confidence that the now well established collaboration is becoming a major factor in improving malaria control on a regional basis and hopefully redressing to a substantial degree the key problem of spread of drug resistance regionally and eventually globally.en_US
dc.description.affiliationCenter for National Malaria Control (CNM), Phnom Penh, Cambodia.en_US
dc.identifier.citationSocheat D, Denis MB, Fandeur T, Zhang Z, Yang H, Xu J, Zhou X, Phompida S, Phetsouvanh R, Lwin S, Lin K, Win T, Than SW, Htut Y, Prajakwong S, Rojanawatsirivet C, Tipmontree R, Vijaykadga S, Konchom S, Cong le D, Thien NT, Thuan le K, Ringwald P, Schapira A, Christophel E, Palmer K, Arbani PR, Prasittisuk C, Rastogi R, Monti F, Urbani C, Tsuyuoka R, Hoyer S, Otega L, Thimasarn K, Songcharoen S, Meert JP, Gay F, Crissman L, Cho-Min-Naing , Chansuda W, Darasri D, Indaratna K, Singhasivanon P, Chuprapawan S, Looareesuwan S, Supavej S, Kidson C, Baimai V, Yimsamran S, Buchachart K. Mekong malaria. II. Update of malaria, multi-drug resistance and economic development in the Mekong region of Southeast Asia. The Southeast Asian Journal of Tropical Medicine and Public Health. 2003 ; 34 Suppl 4(): 1-102en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/33518
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntimalarials --pharmacologyen_US
dc.subject.meshCambodia --epidemiologyen_US
dc.subject.meshChina --epidemiologyen_US
dc.subject.meshCulicidaeen_US
dc.subject.meshDrug Resistance, Multipleen_US
dc.subject.meshEnvironmenten_US
dc.subject.meshHealth Status Indicatorsen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshInsect Vectorsen_US
dc.subject.meshLaos --epidemiologyen_US
dc.subject.meshMalaria --drug therapyen_US
dc.subject.meshMyanmar --epidemiologyen_US
dc.subject.meshPlasmodium falciparum --drug effectsen_US
dc.subject.meshPlasmodium vivax --drug effectsen_US
dc.subject.meshPopulation Densityen_US
dc.subject.meshResidential Mobilityen_US
dc.subject.meshSocioeconomic Factorsen_US
dc.subject.meshThailand --epidemiologyen_US
dc.subject.meshVietnam --epidemiologyen_US
dc.titleMekong malaria. II. Update of malaria, multi-drug resistance and economic development in the Mekong region of Southeast Asia.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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