Inappropriate prescription of allopurinol in a teaching hospital.

dc.contributor.authorAthisakul, Siripornen_US
dc.contributor.authorWangkaew, Suparapornen_US
dc.contributor.authorLouthrenoo, Worawiten_US
dc.date.accessioned2009-05-27T18:41:17Z
dc.date.available2009-05-27T18:41:17Z
dc.date.issued2007-05-29en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractBACKGROUND: Allopurinol is a drug that is widely used to treat hyperuricemia, but it is often prescribed inappropriately. OBJECTIVE: The authors conducted a study to look for the appropriate allopurinol prescription and diagnosis of gout in the out-patient clinics at a university hospital. MATERIAL AND METHOD: One hundred and forty-five patients who were newly prescribed allopurinol (128 males and 17 females, mean +/- SD age of 58.5 +/-14.1 years) were enrolled in this study. RESULT: Only 77 (53.1%) received allopurinol with appropriate indications. Thirty-eight patients (26.2%) did not have allopurinol dose adjustment according to the patients' creatinine clearance. Among 131 patients, prescribed allopurinol for the diagnosis of gout, only 55 (42.0%) were diagnosed in accordance with the American Rheumatism Association criteria. CONCLUSION: Inappropriate use of allopurinol (both the indication and prescribed dosage) and inappropriate diagnosis of gout are major problems even in a large teaching hospital. An educational campaign program is warranted for achieving appropriate diagnosis of gout, and eliminating the inappropriate use of allopurinol.en_US
dc.description.affiliationDivision of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.en_US
dc.identifier.citationAthisakul S, Wangkaew S, Louthrenoo W. Inappropriate prescription of allopurinol in a teaching hospital. Journal of the Medical Association of Thailand. 2007 May; 90(5): 889-94en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/39647
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAgeden_US
dc.subject.meshAllopurinol --therapeutic useen_US
dc.subject.meshDrug Prescriptionsen_US
dc.subject.meshDrug Utilization Reviewen_US
dc.subject.meshFemaleen_US
dc.subject.meshGout Suppressants --therapeutic useen_US
dc.subject.meshHealth Services Misuseen_US
dc.subject.meshHospitals, Teaching --standardsen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperuricemia --diagnosisen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOutpatient Clinics, Hospital --standardsen_US
dc.subject.meshPhysician's Practice Patternsen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshThailanden_US
dc.titleInappropriate prescription of allopurinol in a teaching hospital.en_US
dc.typeJournal Articleen_US
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