Inappropriate prescription of allopurinol in a teaching hospital.
| dc.contributor.author | Athisakul, Siriporn | en_US |
| dc.contributor.author | Wangkaew, Suparaporn | en_US |
| dc.contributor.author | Louthrenoo, Worawit | en_US |
| dc.date.accessioned | 2009-05-27T18:41:17Z | |
| dc.date.available | 2009-05-27T18:41:17Z | |
| dc.date.issued | 2007-05-29 | en_US |
| dc.description | Chotmaihet Thangphaet. | en_US |
| dc.description.abstract | BACKGROUND: Allopurinol is a drug that is widely used to treat hyperuricemia, but it is often prescribed inappropriately. OBJECTIVE: The authors conducted a study to look for the appropriate allopurinol prescription and diagnosis of gout in the out-patient clinics at a university hospital. MATERIAL AND METHOD: One hundred and forty-five patients who were newly prescribed allopurinol (128 males and 17 females, mean +/- SD age of 58.5 +/-14.1 years) were enrolled in this study. RESULT: Only 77 (53.1%) received allopurinol with appropriate indications. Thirty-eight patients (26.2%) did not have allopurinol dose adjustment according to the patients' creatinine clearance. Among 131 patients, prescribed allopurinol for the diagnosis of gout, only 55 (42.0%) were diagnosed in accordance with the American Rheumatism Association criteria. CONCLUSION: Inappropriate use of allopurinol (both the indication and prescribed dosage) and inappropriate diagnosis of gout are major problems even in a large teaching hospital. An educational campaign program is warranted for achieving appropriate diagnosis of gout, and eliminating the inappropriate use of allopurinol. | en_US |
| dc.description.affiliation | Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. | en_US |
| dc.identifier.citation | Athisakul S, Wangkaew S, Louthrenoo W. Inappropriate prescription of allopurinol in a teaching hospital. Journal of the Medical Association of Thailand. 2007 May; 90(5): 889-94 | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/39647 | |
| dc.language.iso | eng | en_US |
| dc.source.uri | https://www.mat.or.th/journal/all.php | en_US |
| dc.subject.mesh | Aged | en_US |
| dc.subject.mesh | Allopurinol --therapeutic use | en_US |
| dc.subject.mesh | Drug Prescriptions | en_US |
| dc.subject.mesh | Drug Utilization Review | en_US |
| dc.subject.mesh | Female | en_US |
| dc.subject.mesh | Gout Suppressants --therapeutic use | en_US |
| dc.subject.mesh | Health Services Misuse | en_US |
| dc.subject.mesh | Hospitals, Teaching --standards | en_US |
| dc.subject.mesh | Humans | en_US |
| dc.subject.mesh | Hyperuricemia --diagnosis | en_US |
| dc.subject.mesh | Male | en_US |
| dc.subject.mesh | Middle Aged | en_US |
| dc.subject.mesh | Outpatient Clinics, Hospital --standards | en_US |
| dc.subject.mesh | Physician's Practice Patterns | en_US |
| dc.subject.mesh | Retrospective Studies | en_US |
| dc.subject.mesh | Thailand | en_US |
| dc.title | Inappropriate prescription of allopurinol in a teaching hospital. | en_US |
| dc.type | Journal Article | en_US |
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