Geographical distribution of hepatitis C virus genotypes in India.

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dc.contributor.authorDas, B Ren_US
dc.contributor.authorKundu, Biduthen_US
dc.contributor.authorKhandapkar, Rashmien_US
dc.contributor.authorSahni, Sumedhaen_US
dc.date.accessioned2002-07-06en_US
dc.date.accessioned2009-05-29T12:31:46Z
dc.date.available2002-07-06en_US
dc.date.available2009-05-29T12:31:46Z
dc.date.issued2002-07-06en_US
dc.description.abstractHCV isolates from around the world show substantial nucleotide sequence variability throughout the viral genome. Based on the identification of these genome differences various genotypes and subtypes have been described from different geographical regions. They have been tentatively classified into six major genotypes and more than 30 subtypes, but new subtypes are continually being discovered. In recent years, substantial evidence has emerged indicating that typing and subtyping for HCV is clinically important. The present study aims at determining and comparing the prevalence of different genotypes from different parts of India (North, South, East and West). A total of 153 samples representing different regions have been genotyped in our lab. Our studies document a high prevalence of genotype 3 (> 76%) and very low prevalence of genotype 2 (< 2%), as a whole. However, genotype 3a has been found to be the highest (50%) with a decreased frequency of approximately 25% in the case of 3b, approximately 14% in 1b and approximately 10% in 1a, whereas a minimal number (approximately 4%) of genotype 4 has been found only in Southern and Western India.en_US
dc.description.affiliationSpecially Ranbaxy Ltd., Clinical Reference Laboratories, Plot 113. M.I.D.C., 15th Street, Andheri (East), Mumbai.en_US
dc.identifier.citationDas BR, Kundu B, Khandapkar R, Sahni S. Geographical distribution of hepatitis C virus genotypes in India. Indian Journal of Pathology & Microbiology. 2002 Jul; 45(3): 323-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/74687
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshGenotypeen_US
dc.subject.meshHepacivirus --classificationen_US
dc.subject.meshHepatitis C --diagnosisen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshRNA, Viral --geneticsen_US
dc.titleGeographical distribution of hepatitis C virus genotypes in India.en_US
dc.typeJournal Articleen_US
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