Percutaneous coronary intervention (PCI) in patients of rheumatoid arthritis(RA): A systematic review and meta-analysis

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dc.contributor.authorPiplani, Shobhiten_US
dc.contributor.authorKostojchin, Anastasen_US
dc.contributor.authorKong, Steveen_US
dc.contributor.authorSharma, Aakankshaen_US
dc.contributor.authorBrown, Donclairen_US
dc.contributor.authorJelic, Vladimiren_US
dc.contributor.authorChaturvedi, Salilen_US
dc.contributor.authorReddy, Vishalen_US
dc.contributor.authorPieri, Katherine Changen_US
dc.contributor.authorAkpan, Ezekielen_US
dc.contributor.authorSimpson, Tamaraen_US
dc.contributor.authorXiao, Wenzhenen_US
dc.contributor.authorSakellakis, Minasen_US
dc.contributor.authorSharma, Aayushien_US
dc.contributor.authorJain, Priyanshuen_US
dc.contributor.authorRadulovic, Miroslaven_US
dc.date.accessioned2025-06-18T11:10:18Z
dc.date.available2025-06-18T11:10:18Z
dc.date.issued2025-02
dc.description.abstractAim: The present study aims to investigate the outcomes of Percutaneous coronary intervention (PCI) in patients with Rheumatoid arthritis (RA). Methods: A systemic search was conducted from electronic databases (PubMed/Medline, Cochrane Library, and Google Scholar) from inception to 15th September 2023. All statistical analyses were conducted using Review Manager 5.4.1. Studies meeting inclusion criteria were selected. A random-effect model was used when het- erogeneity was seen to pool the studies, and the result was reported in the odds ratio (OR) and the corresponding 95 % confidence interval (CI). Results: Eight observational studies were selected to conduct the analysis. A statistically significant increase in major adverse cardiovascular event (MACE) was seen in RA patients after undergoing PCI as compared to the control group (OR = 1.18 (1.16, 1.21); p < 0.00001; I2 = 0 %). There was no significant difference found in the long-term revascularization outcome between the RA and non-RA patients (OR = 1.18 (0.81, 1.71); p = 0.39; I2 = 93 %). Survival rates of all-cause mortality in the long-term outcome were statistically insignificant among the two groups (OR = 1.21 (0.84, 1.74); p = 0.31; I2 = 99 %). Conclusion: Percutaneous coronary intervention is an important intervention to reduce morbidity and mortality but special precautions and attention should be made when it comes to patients with RA. Different precautions such as close monitoring for medication interaction, and tailored post-procedural care are essential in reducing morbidity and mortality.en_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsDepartment of Cardiology North Central Bronx Hospital/VA Medical Center, Icahn School of Mount Sinai, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsDepartment of Cardiology, Yale School of Medicine, New Haven, CT, 333 Cedar Street, New Haven, CT, 06510, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.affiliationsDepartment of Internal Medicine, Jawaharlal Nehru Medical College, Belagavi, Karnataka, 590010, Indiaen_US
dc.identifier.affiliationsJacobi Medical Center/North Central Bronx, Albert Einstein College of Medicine, NYC Health and Hospitals, 3424 Kossuth Avenue, Bronx, NY, 10467, USAen_US
dc.identifier.citationPiplani Shobhit, Kostojchin Anastas, Kong Steve, Sharma Aakanksha, Brown Donclair, Jelic Vladimir, Chaturvedi Salil, Reddy Vishal, Pieri Katherine Chang, Akpan Ezekiel, Simpson Tamara, Xiao Wenzhen, Sakellakis Minas, Sharma Aayushi, Jain Priyanshu, Radulovic Miroslav . Percutaneous coronary intervention (PCI) in patients of rheumatoid arthritis(RA): A systematic review and meta-analysis. Indian Heart Journal. 2025 Feb; 77(1): 7-13en_US
dc.identifier.issn0019-4832
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/248304
dc.languageenen_US
dc.publisherElsevieren_US
dc.relation.issuenumber1en_US
dc.relation.volume77en_US
dc.source.urihttps://doi.org/10.1016/j.ihj.2024.12.002en_US
dc.subjectPercutaneous coronary interventionen_US
dc.subjectRheumatoid arthritisen_US
dc.subjectConnective tissue disordersen_US
dc.subjectCoronary revascularizationen_US
dc.titlePercutaneous coronary intervention (PCI) in patients of rheumatoid arthritis(RA): A systematic review and meta-analysisen_US
dc.typeJournal Articleen_US
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