Nano technology: A review.
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Date
2011-04
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Abstract
The recent research on bio-systems at the nano-scale and the nanotechnology has
created one of the most dynamic science and technology domains at the confluence of physical
sciences, molecular engineering, biology, biotechnology and medicine. This domain includes
better understanding of living and thinking systems, revolutionary biotechnology processes,
synthesis of new drugs and their targeted delivery, regenerative medicine, neuromorphic
engineering and developing a sustainable environment. Nano bio-systems research is a priority in
many countries and its relevance within nanotechnology is expected to increase in the future. The
reduction of drug particles into the sub-micron range leads to a significant increase in the
dissolution rate and therefore enhances bioavailability. There has been a considerable research
interest in the area of developing drug delivery using nanoparticles (NP’s) as carriers for small
and large molecules. Targeting delivery of drugs to the diseased lesions is one of the most
important aspects of drug delivery system. They have been used in-vivo to protect the drug entity
in the systemic circulation, restrict access of the drug to the chosen sites and to deliver the drug
at a controlled and sustained rate to this site of action. Various polymers have been used in the
formulation of nanoparticles for drug delivery research to increase therapeutic benefit, while
minimizing the side-effects. This review article presents the most outstanding contributions in
the field of nanotechnology as drug delivery system. Pharmaceutical nanotechnology based
systems, methods of preparation, applications, advantages and disadvantages.
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Keywords
Nanotechnology, Nanoparticles, Nano-systems, Nanodevices, Nanotubes
Citation
Rangasamy Manivannan. Nano technology: A review. Journal of Applied Pharmaceutical Science. 2011 Apr; 1(2): 8-16.