The newborn with seizures -- a follow-up study.

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dc.contributor.authorIype, Maryen_US
dc.contributor.authorPrasad, Mayaen_US
dc.contributor.authorNair, P M Cen_US
dc.contributor.authorGeetha, Sen_US
dc.contributor.authorKailas, Lalithaen_US
dc.date.accessioned2008-09-30en_US
dc.date.accessioned2009-05-27T06:15:23Z
dc.date.available2008-09-30en_US
dc.date.available2009-05-27T06:15:23Z
dc.date.issued2008-09-30en_US
dc.description.abstractOBJECTIVE: To determine the sequelae of neonatal seizures in a cohort of newborns, recruited over a six month period. DESIGN: Prospective hospital based study. SETTING: The neonatal intensive care unit (NICU) of a tertiary care hospital. PARTICIPANTS: 135 babies were recruited of whom 10 died and 25 were lost to follow up. METHODS: The cases were followed up over four months. RESULTS: 68% of the babies followed up were normal; 32% had an abnormal neurological outcome. Seven (7%) developed post-neonatal epilepsy. Hypocalcemia was significantly associated with mortality (OR: 21.9; 95% CI: 1.2-391.2). No risk factors could be identified for post neonatal epilepsy. Presence of spike waves in the EEG was significantly related to abnormal neurological outcome (OR: 3.5; 95% C.I. 1.2-10.8). CONCLUSIONS: Majority of neonates with seizures have a normal outcome with no developmental delay or neurological deficit. Predominantly spike waves in the EEG is predictive of abnormal neurological outcome.en_US
dc.description.affiliationDepartment of Neurology and Pediatrics, SAT Hospital, Medical College Trivandrum, Kerala, India. tvm_agkoshy@sancharnet.inen_US
dc.identifier.citationIype M, Prasad M, Nair PM, Geetha S, Kailas L. The newborn with seizures -- a follow-up study. Indian Pediatrics. 2008 Sep; 45(9): 749-52en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/15749
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshDevelopmental Disabilities --epidemiologyen_US
dc.subject.meshEpilepsy --epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshNervous System Diseases --epidemiologyen_US
dc.subject.meshPrognosisen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSeizures --complicationsen_US
dc.titleThe newborn with seizures -- a follow-up study.en_US
dc.typeJournal Articleen_US
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