Early recombinant factor VIIa therapy in acute intracerebral hemorrhage: promising approach.

dc.contributor.authorKumar, Sudhiren_US
dc.contributor.authorBadrinath, H Ren_US
dc.date.accessioned2006-03-09en_US
dc.date.accessioned2009-06-03T12:18:48Z
dc.date.available2006-03-09en_US
dc.date.available2009-06-03T12:18:48Z
dc.date.issued2006-03-09en_US
dc.description21 references.en_US
dc.description.abstractIntracerebral hemorrhage (ICH) is the most devastating form of stroke with a high morbidity and mortality. ICH constitutes about 20-30% of all strokes, with the prevalence being higher in Asian population. Treatment of ICH is predominantly conservative, which includes control of blood pressure, use of anti-cerebral edema measures such as mannitol and mechanical ventilation. The benefit of early surgery in ICH is debatable. Initial hematoma volume and subsequent growth in its size are important predictors of a poor outcome in ICH. This means that therapies aimed at preventing hematoma enlargement in the earliest possible window period could lead to a better outcome in ICH. Recombinant factor VIIa (rFVIIa) is one such agent, which has been shown to prevent hematoma expansion and improve outcome in acute ICH. The purpose of the current review is to focus on the evidence regarding the usefulness of rFVIIa in acute ICH.en_US
dc.description.affiliationDepartment of Neurological Sciences, Apollo Hospitals, Hyderabad - 500 033, India. drsudhirkumar@yahoo.comen_US
dc.identifier.citationKumar S, Badrinath HR. Early recombinant factor VIIa therapy in acute intracerebral hemorrhage: promising approach. Neurology India. 2006 Mar; 54(1): 24-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/121470
dc.language.isoengen_US
dc.source.urihttps://neurologyindia.comen_US
dc.subject.meshCerebral Hemorrhage --drug therapyen_US
dc.subject.meshClinical Trials as Topicen_US
dc.subject.meshFactor VIIa --therapeutic useen_US
dc.subject.meshHumansen_US
dc.subject.meshRecombinant Proteins --therapeutic useen_US
dc.titleEarly recombinant factor VIIa therapy in acute intracerebral hemorrhage: promising approach.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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