Factors affecting carotid intimal medial thickness in patients with rheumatoid arthritis, an analytical cross-sectional study

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dc.contributor.authorPrabhuswamy, K. M.en_US
dc.contributor.authorJoena, M. Virginen_US
dc.date.accessioned2020-04-09T07:41:55Z
dc.date.available2020-04-09T07:41:55Z
dc.date.issued2019-05
dc.description.abstractBackground: IMT assessment as a non-invasive imaging test is quite widely used especially among RA patients, the clinical applications of using such knowledge is scarce, hence study was conducted to compare the carotid artery intima-media thickness (CIMT) in patients with rheumatoid arthritis (RA) with healthy controls also to study the correlation between duration of rheumatoid arthritis, the activity of rheumatoid arthritis and other factors influencing (CIMT).Methods: In analytical cross-sectional study, of 80 participants of RA and 40 healthy controls, “DAS28” was used to assess disease activity. Carotid intima-media thickness assessed using carotid ultrasonography.Results: Mean age of the cases and controls was 43.9 and 44.38 years. Subjects with duration of disease <2 years, to 5 years and >5 years were 35%, 45% and 20%. The mean carotid intima-media thickness was 5.61mm in controls, and CIMT was 6.11mm in people below 2 years and 7.08 mm in people between 2 to 5 years and 8.00mm in people above 5 years which was statistically significant. The mean carotid intima-media thickness was 5.61mm controls and 6.86mm in people with low, 7.00mm in people with moderate and 6.95mm in people with high disease activity, which was statistically significant.Conclusions: Study findings revealed risk of increase in carotid intima-media thickness higher among RA patients in the later stages and can increase the patients’ susceptibility to cardiovascular events. The factors showing strong association with intimal medial thickness were the age and symptoms duration.en_US
dc.identifier.affiliationsDepartment of General Medicine, Velammal Medical College and Research Institute, Madurai, Tamil Nadu, Indiaen_US
dc.identifier.citationPrabhuswamy K. M., Joena M. Virgin. Factors affecting carotid intimal medial thickness in patients with rheumatoid arthritis, an analytical cross-sectional study. International Journal of Advances in Medicine. 2019 May; 6(3): 628-633en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/194265
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20191473en_US
dc.subjectCIMTen_US
dc.subjectDAS28en_US
dc.subjectIMTen_US
dc.subjectRAen_US
dc.titleFactors affecting carotid intimal medial thickness in patients with rheumatoid arthritis, an analytical cross-sectional studyen_US
dc.typeJournal Articleen_US
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