Effect of garlic pretreatment on isoprenaline-induced myocardial necrosis in albino rats.

Simple item page
dc.contributor.authorSaxena, K Ken_US
dc.contributor.authorGupta, Ben_US
dc.contributor.authorKulshrestha, V Ken_US
dc.contributor.authorSrivastava, R Ken_US
dc.contributor.authorPrasad, D Nen_US
dc.date.accessioned1980-07-01en_US
dc.date.accessioned2009-06-01T06:36:20Z
dc.date.available1980-07-01en_US
dc.date.available2009-06-01T06:36:20Z
dc.date.issued1980-07-01en_US
dc.description.abstractAlbino rats were pretreated orally for seven days with different doses of the essential oil and juice of garlic. These animals were challenged with isoprenaline (85 mg/kg, s.c.) on day six and seven to induce myocardial necrosis. The same rats were also subjected to swimming test before and after forty eight hr of first injection of isoprenaline. Pretreatment with essential oil (2.0 and 4.0 mg/kg) and juice (2.0 and 4.0 ml/kg) significantly protected the myocardium from isoprenaline-induced necrosis. These animals also exhibited better swimming performance. In separate group of animals, pretreatment with garlic juice (4.0 ml/kg) or essential oil (4.0 mg/kg) improved the chances of survival in isoprenaline-challenged animals.en_US
dc.identifier.citationSaxena KK, Gupta B, Kulshrestha VK, Srivastava RK, Prasad DN. Effect of garlic pretreatment on isoprenaline-induced myocardial necrosis in albino rats. Indian Journal of Physiology and Pharmacology. 1980 Jul-Sep; 24(3): 233-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/107515
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCardiomyopathies --chemically induceden_US
dc.subject.meshGarlicen_US
dc.subject.meshIsoproterenol --pharmacologyen_US
dc.subject.meshMyocardium --pathologyen_US
dc.subject.meshNecrosis --chemically induceden_US
dc.subject.meshOils, Volatile --pharmacologyen_US
dc.subject.meshPlants, Medicinalen_US
dc.subject.meshRatsen_US
dc.titleEffect of garlic pretreatment on isoprenaline-induced myocardial necrosis in albino rats.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Physiology and Pharmacology