Arginase from rat fibrosarcoma. Its possible role in proline, glutamate and polyamine metabolism.
| dc.contributor.author | Gopalakrishna, R | |
| dc.contributor.author | Nagarajan, B | |
| dc.date.accessioned | 2015-07-18T09:37:16Z | |
| dc.date.available | 2015-07-18T09:37:16Z | |
| dc.date.issued | 1980-12 | |
| dc.description.abstract | The presence of arginase in rat fibrosarcoma not synthesizing urea, suggested that this enzyme may have additional functions. Ornithine carbamoyl transferase, a key enzyme of the urea cycle was absent in this tissue, when compared to normal tissues, lower amount of ornithine was found in the fibrosarcoma, but this tumour contained a higher level of proline. The radioactivity present in L-[U-14C] arginine was incorporated into putrescine, spermidine, spermine, proline glutamate and glutamine suggesting that arginine was a possible precursor and that arginase may have a role in the synthesis of these metabolites. | en_US |
| dc.identifier.citation | Gopalakrishna R, Nagarajan B. Arginase from rat fibrosarcoma. Its possible role in proline, glutamate and polyamine metabolism. Journal of Biosciences. 1980 Dec; 2(4): 275-282. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/160027 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.ias.ac.in/jarch/jbiosci/2/275-282.pdf | en_US |
| dc.subject | Rat fibrosarcoma | en_US |
| dc.subject | arginase | en_US |
| dc.subject | ornithine carbamoyl transferase | en_US |
| dc.subject | polyamines | en_US |
| dc.subject | proline | en_US |
| dc.subject | glutamate | en_US |
| dc.title | Arginase from rat fibrosarcoma. Its possible role in proline, glutamate and polyamine metabolism. | en_US |
| dc.type | Article | en_US |