Pulmonary nocardiosis due to nocardia farcinica in a renal transplant recipient.

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dc.contributor.authorGowrinath, K
dc.contributor.authorBaig, Waqas Wahid
dc.contributor.authorPrabhu, Attur Ravindra
dc.contributor.authorChawla, Kiran
dc.contributor.authorBairy, Indira
dc.date.accessioned2012-05-30T07:20:04Z
dc.date.available2012-05-30T07:20:04Z
dc.date.issued2009-10
dc.description.abstractNocardia farcinica is an infrequent cause of nocardiosis among the renal transplant recipients and it has not been reported so far from India. We report a case of pulmonary nocardiosis due to N. farcinica in a 32-year-old woman with hypothyroidism and post-renal transplant status, currently on immunosuppressive therapy (prednisolone, azathioprine and tacrolimus). The N. farcinica isolate was susceptible to trimethoprim-sulfamethoxazole (TMP-SMZ), linezolid, imipenem, gentamicin but resistant to ceftriaxone, ciprofloxacin, tobramycin, erythromycin, amoxycillin-clavulanic acid and tetracycline. Treatment with TMP-SMZ and linezolid resulted in marked clinico-radiological improvement but after two weeks both of the drugs had to be stopped due to severe pancytopenia as adverse effect of their use. Currently, the patient is on imipenem and remains stable after four weeks of treatment. In N. farcinica infections, multi antibiotic resistance and toxicity of some specific drugs enhances the risk of therapeutic failure in renal transplant recipients.en_US
dc.identifier.citationGowrinath K, Baig Waqas Wahid, Prabhu Attur Ravindra, Chawla Kiran, Bairy Indira. Pulmonary nocardiosis due to nocardia farcinica in a renal transplant recipient. The Indian Journal of Chest Diseases and Allied Sciences, 2009 Oct; 51(4): 237-239.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/138753
dc.language.isoenen_US
dc.source.urihttps://medind.nic.in/iae/t09/i4/iaet09i4p237.pdfen_US
dc.subjectNocardiosisen_US
dc.subjectNocardia farcinicaen_US
dc.subjectRenal transplantationen_US
dc.subjectChemotherapyen_US
dc.subjectTrimethoprim-Sulfamethoxazoleen_US
dc.subjectLinezoliden_US
dc.subject.meshAdult
dc.subject.meshDiagnosis, Differential
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshKidney Failure, Chronic --surgery
dc.subject.meshKidney Transplantation --adverse effects
dc.subject.meshLung Diseases --diagnosis
dc.subject.meshLung Diseases --etiology
dc.subject.meshLung Diseases --microbiology
dc.subject.meshNocardia --isolation & purification
dc.subject.meshNocardia Infections --diagnosis
dc.subject.meshNocardia Infections --etiology
dc.subject.meshNocardia Infections --transmission
dc.subject.meshRadiography, Thoracic
dc.subject.meshSputum --microbiology
dc.titlePulmonary nocardiosis due to nocardia farcinica in a renal transplant recipient.en_US
dc.typeArticleen_US
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