CSI clinical practice guidelines for dyslipidemia management: Executive summary

Abstract
Dyslipidemias are the most important coronary artery disease (CAD) risk factor. Proper management of dyslipidemia is crucial to control the epidemic of premature CAD in India. Cardiological Society of India strived to develop consensus-based guidelines for better lipid management for CAD prevention and treatment. The executive summary provides a bird's eye-view of the CSI: Clinical Practice Guidelines for Dyslipidemia Management published in this issue of the Indian Heart Journal. The summary is focused onthe busy clinician and encourages evidence-based management of patients and high-risk individuals. The summary has serialized various aspects of lipid management including epidemiology and categorization of CAD risk. The focus is on management of specific dyslipidemias relevant to India-raised low density lipoprotein (LDL) cholesterol, non-high density lipoprotein cholesterol (non-HDL-C), apolipoproteins, triglycerides and lipoprotein(a). Drug therapies for lipid lowering (statins, non-statin drugs and other pharmaceutical agents) and lifestyle management (dietary interventions, physical activity and yoga) are summarized. Management of dyslipidemias in oft-neglected patient phenotypes-the elderly, young and children, and patients with comorbidities-stroke, peripheral arterial disease, kidney failure, posttrans- plant, HIV (Human immunodeficiency virus), Covid-19 and familial hypercholesterolemia is also pre- sented. This consensus statement is based on major international guidelines (mainly European) and expert opinion of lipid management leaders from India with focus on the dictum: earlier the better, lower the better, longer the better and together the better. These consensus guidelines cannot replace the indi- vidual clinician judgement who remains the sole arbiter in management of the patient.
Description
Keywords
Dyslipidemia, LDL cholesterol
Citation
Sawhney Jitendra PS., Ramakrishnan Sivasubramanian, Madan Kushal, Ray Saumitra, Jayagopal P Balagopalan, Prabhakaran Dorairaj, Nair Tiny, Zachariah Geevar, Jain Peeyush, Dalal Jamshed, Radhakrishnan Sitaraman, Chopra Arun, Kalra Sanjay, Mehta Ashwani, Pancholia Arvind K., Kabra Nitin K., Kahali Dhiman, Ghose Tapan, Yadav Satyavir, Kerkar Prafulla, Yadav Ajay, Roy Debabrata, Das Mrinal Kanti, Bang Vijay H., Rath Pratap Chandra, Sinha Dhurjati Prasad, Banerjee P.S., Yadav Rakesh, Gupta Rajeev . CSI clinical practice guidelines for dyslipidemia management: Executive summary. Indian Heart Journal. 2024 Mar; 76(1): 6-19