Spectrum of Secondary Glomerular Diseases in Adult Nephrotic Syndrome.

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dc.contributor.authorShashank, Devarasettyen_US
dc.contributor.authorSingh, Mohinien_US
dc.contributor.authorRamakrishnan, S.R.en_US
dc.date.accessioned2020-11-18T10:25:20Z
dc.date.available2020-11-18T10:25:20Z
dc.date.issued2020-07
dc.description.abstractBackground: In developing countries like India, thecauses for end stage renal failure has been changingwith glomerular diseases occupying an important place.The trend of various primary and secondary causes ofNephrotic Syndrome (NS) over the past few decadeshas been debatable especially with reference togeographical locations. Aim and Objectives: This studywas intended to find out the histologic patterns ofglomerular disease associated with NS in South Indiaand analyze the corresponding clinical and biochemicalabnormalities associated with these conditions.Material and Methods: One hundred eighty eightpatients in the age group of 18-80 years with NS whounderwent renal biopsy between the periodst thfrom1 January 2018 to 30 September 2019 wereincluded in this study. Baseline investigations and otherinvestigations related to renal profile evaluationincluding complement levels and HIV antibody weredone. Results: Focal Segmental Glomerulosclerosis(FSGS) accounted for the majority (25.5%) amongprimary glomerular diseases while among thesecondary glomerular diseases Lupus Nephritis (LN)(51.19%) constituted the majority and a substantialcontribution from Human Immunodeficiency VirusAssociated Nephropathy (HIVAN). LN was seen onlyin female patients with a mean age of 33.36 ± 10.74years. Among LN, Class III was the most predominantwhile Class IIIC was less frequent. C3 and C4complement levels were less than normal in Class IVand Class variants of LN. Conclusion: This studyhighlights the spectrum of Lupus Nephritis and HIVassociated nephropathy as a cause for adult NS in atertiary care center in South Indiaen_US
dc.identifier.affiliationsDepartment of General Medicine, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai-600116 (Tamil Nadu) Indiaen_US
dc.identifier.citationShashank Devarasetty, Singh Mohini, Ramakrishnan S.R.. Spectrum of Secondary Glomerular Diseases in Adult Nephrotic Syndrome.. Journal of Krishna Institute of Medical Sciences University. 2020 Jul; 9(3): 1-9en_US
dc.identifier.issn2231-4261
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/215659
dc.languageenen_US
dc.publisherKrishna Institute of Medical Sciences Universityen_US
dc.relation.issuenumber3en_US
dc.relation.volume9en_US
dc.source.urihttps://www.jkimsu.com/jkimsu-vol9no3/JKIMSU,%20Vol.%209,%20No.%203,%20July-September%202020%20Page%201-9.pdfen_US
dc.subjectNephrotic Syndromeen_US
dc.subjectPrimary Glomerular diseaseen_US
dc.subjectSecondary Glomerular diseaseen_US
dc.subjectLupus Nephritisen_US
dc.subjectHIVAssociated Nephropathyen_US
dc.titleSpectrum of Secondary Glomerular Diseases in Adult Nephrotic Syndrome.en_US
dc.typeJournal Articleen_US
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