To Assess the Safety and Efficacy of Misoprostol Administered Sublingually For Induction of Labour in Patient with PROM with Poor Bishop’s Score

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dc.contributor.authorRathore, Sushma Singhen_US
dc.contributor.authorParmar, Monikaen_US
dc.date.accessioned2020-09-24T07:24:51Z
dc.date.available2020-09-24T07:24:51Z
dc.date.issued2019-03
dc.description.abstractBackground: The management of PROM has often been adilemma in obstetrics. Different regimens are followed indifferent centres all over the world for management of PROM.This study is aimed to compare the safety and efficacy ofsublingually equivalent dose regimen administered vaginally forinduction of labour in patient with PROM with poor Bishop’sScore.Material & Methods: A prospective randomised controlled trialdone on 60 Patients of PROM admitted in labour room ofGovernment Medical College, Dungarpur, as per inclusion andexclusion criteria. Group 1- Received 25µg misoprostol,intravaginally 4 hourly up to maximum of 3 doses, placed inposterior fornix. Group 2- Received 25 µg misoprostol,sublingually 4 hourly up to maximum of 3 doses. Foetal heartand labour progress monitoring was done. Before every dose apervaginum examination was performed to assess the Bishopscore.Results: Our study showed that the foetal distress (foetal heartrate (FHR) abnormalities; FB<120bpm, FT >160bpm) wasmost common intrapartum complication in both groups(13.33% each). Mean induction delivery interval in sublingualgroup was 8.13±4.29 hours and in intravaginal group was7.31±4.11hours. Majority of women in both groups deliveredvaginally; 25 patients (83.33%) in intravaginal and 26 patients(86.66%) in sublingual group. 2 patients in intravaginal and 1patient in sublingual group had atonic PPH. However nopatient required blood transfusion. None had retained placenta.There was no maternal mortality.Conclusion: We concluded that both sublingual andintravaginal route of administration of 25µg misoprostol areequally effective in achieving favourable Bishop’s score,vaginal delivery rates, with comparable induction to deliveryintervals without increasing the caesarean rates and thepostpartum complications.en_US
dc.identifier.affiliationsSenior Demonstrator, Department of Pathology, Government Medical College, Dungarpur, Rajasthan, Indiaen_US
dc.identifier.affiliationsAssociate Professor, Department of Obstetrics & Gynaecology, Government Medical College, Dungarpur, Rajasthan, India.en_US
dc.identifier.citationRathore Sushma Singh, Parmar Monika. To Assess the Safety and Efficacy of Misoprostol Administered Sublingually For Induction of Labour in Patient with PROM with Poor Bishop’s Score. International Journal of Medical Research Professionals. 2019 Mar; 5(2): 204-207en_US
dc.identifier.issn2454-6364
dc.identifier.issn2454-6356
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203146
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber2en_US
dc.relation.volume5en_US
dc.source.urihttps://dx.doi.org//10.21276/ijmrp.2019.5.2.042en_US
dc.subjectPROMen_US
dc.subjectBishop’s Scoreen_US
dc.subjectMisoprostolen_US
dc.subjectSublingualen_US
dc.subjectIntravaginal.en_US
dc.titleTo Assess the Safety and Efficacy of Misoprostol Administered Sublingually For Induction of Labour in Patient with PROM with Poor Bishop’s Scoreen_US
dc.typeJournal Articleen_US
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