Hypoadiponectinemia: a risk factor for metabolic syndrome.

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dc.contributor.authorRenaldi, Ollyen_US
dc.contributor.authorPramono, Bowoen_US
dc.contributor.authorSinorita, Hemien_US
dc.contributor.authorPurnomo, Luthfan Budien_US
dc.contributor.authorAsdie, Rizka Humardewayantien_US
dc.contributor.authorAsdie, Ahmad Hen_US
dc.date.accessioned2009-01-05en_US
dc.date.accessioned2009-05-28T04:35:21Z
dc.date.available2009-01-05en_US
dc.date.available2009-05-28T04:35:21Z
dc.date.issued2009-01-05en_US
dc.description.abstractAim: to find out correlation between plasma adiponectin levels, insulin resistance and IDF criteria of Mets Patients. Methods: a case-control study was conducted on Native Javanese people from June 2006 to Januari 2007 in Outpatients Clinic of Dr Sardjito Hospital. The case group involved patients aged between 20 to 55 years old. The diagnosis of metabolic syndrome was confirmed according to IDF criteria. Patients without metabolic syndrome with matching age and sex,were taken as control group. Results: there were significant differences between case andh control group for BMI (body mass index) (30.2 +/- 4.1 vs 26.9 +/- 4.7 kg/m2), waist circumference (93.5 +/- 7.9 vs 84.4 +/- 11.5 cm), triglyceride (207.4 +/- 101.8 vs. 119.3 +/- 71.5 mg/dL) , HDL cholesterol (48.6 +/- 9.4 vs. 59.9 +/- 11.8m g/dL), systolic blood pressure (132.8 +/- 17.9mmHg vs 120.6 +/- 13.5 mmHg) and diastolic blood pressure (83.8 +/- 8.5 mmHg vs. 79.4 +/- 10.7), fasting blood glucose (128.3 +/- 40.8 mg/dL vs. 100.7 +/- 29.4 mg/dL), HOMA index (6.7 +/- 17.4 vs. 2.0 +/- 2.0) and adiponectin levels (3.8 +/- 1.4 vs. 5.9 +/- 2.5), respectively. For metabolic syndrome, hypoadiponectinemia showed the OR value of 6.0 (95% CI 2.13 to 16.98); insulin resistance showed the OR value of 5.7 (95% CI 1.3 to 25.02), after adjustment for waist circumference, TG, HLD, blood pressure, fasting blood glucose. Conclusion: hypoadiponectinemia and insulin resistance represent independent risk factors for metabolic syndrome development.en_US
dc.description.affiliationDepartment of Internal Medicine, Faculty of Medicine Gadjah Mada University-Dr. Sardjito Hospital. Jl. Kesehatan Sekip no.1, Yogyakarta.en_US
dc.identifier.citationRenaldi O, Pramono B, Sinorita H, Purnomo LB, Asdie RH, Asdie AH. Hypoadiponectinemia: a risk factor for metabolic syndrome. Acta Medica Indonesiana. 2009 Jan; 41(1): 20-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/47119
dc.language.isoengen_US
dc.subject.meshAdiponectinen_US
dc.subject.meshMetabolism, Inborn Errorsen_US
dc.titleHypoadiponectinemia: a risk factor for metabolic syndrome.en_US
dc.typeJournal Articleen_US
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