Pure malignant myoepitheliomas of the breast: an immunohistochemical study.

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dc.contributor.authorKapoor, Neelkamalen_US
dc.contributor.authorChinoy, Roshni Fen_US
dc.date.accessioned2006-04-29en_US
dc.date.accessioned2009-05-29T13:28:01Z
dc.date.available2006-04-29en_US
dc.date.available2009-05-29T13:28:01Z
dc.date.issued2006-04-29en_US
dc.description.abstractMyoepithelioma of breast are extremely rare. We report two cases of pure malignant myoepithelioma of the breast, utilising light microscopic and immunohistochemical methods for diagnosis. Both the cases presented as breast lump. Hematoxylin and Eosin (H&E) stained microscopic sections revealed a predominantly spindle cell tumor. Immunohistochemical work up was done. Case number one expressed positivity for vimentin, Smooth Muscle Actin (SMA), S-100 and CD10. Case number two expressed positivity for Vimentin, CD10 and p63. This led to the diagnoses of malignant myoepithelioma in both of them. Documentation of such cases prospectively and from archival material, using immunohistochemistry, is of extreme importance to assess the prevalence, various phenotypic patterns, long-term biological behaviour and to establish management protocols for malignant myoepithelioma.en_US
dc.description.affiliationDepartment Of Pathology, Gandhi Medical College, Bhopal and Tata Memorial Hospital, Mumbai. nkapoorn@rediffmail.comen_US
dc.identifier.citationKapoor N, Chinoy RF. Pure malignant myoepitheliomas of the breast: an immunohistochemical study. Indian Journal of Pathology & Microbiology. 2006 Apr; 49(2): 279-81en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/75678
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshActins --metabolismen_US
dc.subject.meshBreast Neoplasms --diagnosisen_US
dc.subject.meshDNA-Binding Proteins --metabolismen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunohistochemistryen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMyoepithelioma --diagnosisen_US
dc.subject.meshNeprilysin --metabolismen_US
dc.subject.meshS100 Proteins --metabolismen_US
dc.subject.meshTrans-Activators --metabolismen_US
dc.subject.meshTumor Suppressor Proteins --metabolismen_US
dc.subject.meshVimentin --metabolismen_US
dc.titlePure malignant myoepitheliomas of the breast: an immunohistochemical study.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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