Beta Thalassemia Major with Diabetes Mellitus: A Case Report

Thalassemia occurs due to defects in normal hemoglobin production. Globally it is most common inherited anaemia. Diabetes is a complication of b-thalassemia major. We report a case of Diabetes mellitus in a known case of beta thalassemia major. Patient had undergone splenectomy 1 year back. Patient is taking chelating agent Defasirox 1000mg orally once a day in the morning. Family history reveals, born through third degree consanguineous marriage. The patient was then subjected for laboratory examination reveals BSLwas 490, urine ketone 2+, urine sugar 3+, ABG was normal, HbA1c was 13 & 3 month old report of serum ferritin 1200 ng/dl. TFTand GH studies normal. Multidisciplinary management was instituted. Blood sugar level got controlled over subcutaneous insulin. Patient may have landed in Diabetic ketoacidosis but was promptly diagnosed & treated. This case is presented for its rarity. Due to increase in life expectancy of patient with thalassemia major, patient will expose more years of hyperglycemia and diabetes. Sustaining metabolic control and controlling cardiovascular risk factors helps to prevent future complications.

Keywords

Thalassemia, Diabetes Mellitus, Iron chelation, Blood transfusion, Hyperglycemia

Citation

Mhaske Dr. Sneha, Shinde Dr. Abhijit, Shinde Dr. Sonal, Kothari Dr. Ramesh, Misal Dr. Ganesh, Kumar Dr. Sushruta, Mhaske Prof. Dr. Sunil Natha. Beta Thalassemia Major with Diabetes Mellitus: A Case Report. VIMS Health Science Journal. 2021 Jun; 8(2): 85-88

URI

https://imsear.searo.who.int/handle/123456789/219051

Collections

VIMS Health Science Journal (VIMSHSJ)

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