Isolation, characterization, and cytotoxic studies of secondary metabolites from the leaves of Bauhinia foveolata Dalzell: An endemic tree from the Western Ghats, India

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dc.contributor.authorHabbu, Prasanna V.en_US
dc.contributor.authorMiskin, Narayanen_US
dc.contributor.authorVenkatrao, H. Kulkarnien_US
dc.contributor.authorBhat, Pradeepen_US
dc.contributor.authorJoshi, Arunen_US
dc.contributor.authorBhandarkar, Ananten_US
dc.contributor.authorKulkarni, Satishen_US
dc.contributor.authorDixit, Sheshagiri R.en_US
dc.contributor.authorVaijanathappa, Jaishreeen_US
dc.date.accessioned2020-10-16T08:56:51Z
dc.date.available2020-10-16T08:56:51Z
dc.date.issued2020-03
dc.description.abstractBauhinia foveolata Dalzell is an endemic tree, native to Southwest India (the Western Ghats). 13-Docosenamide wasisolated from ethyl acetate fraction, and quercetin (1), isorhamnetin (2), and odoratin-7-glucoside (3) were isolatedfrom butanol fraction of leaves. A spectroscopic analysis, including mass spectra and Nuclear Magnetic Resonance(NMR), and also comparison with reported data were used to elucidate the chemical structures of isolated compounds.Furthermore, all the isolated compounds were analyzed for 3-(4, 5-dimethylthiazol-2-yl)-5-diphenyltetrazoliumbromide -based cytotoxicity studies on human colon cancer cell lines, HT-29 and HCT-15; among all the testedcompounds, quercetin and odoratin-7-glucoside have shown a good cytotoxicity toward the selected cell lines.en_US
dc.identifier.affiliationsPostgraduate Department of Pharmacognosy and Phytochemistry, SET’s College of Pharmacy, Dharwad 580 002, India.en_US
dc.identifier.affiliationsPostgraduate Department of Pharmacognosy and Phytochemistry, SET’s College of Pharmacy, Dharwad 580 002, India.en_US
dc.identifier.affiliationsPostgraduate Department of Pharmacology, SET’s College of Pharmacy, Dharwad 580 002, India.en_US
dc.identifier.affiliationsIndian Council of Medical Research, National Institute of Traditional Medicine, Belagavi 590 010, India.en_US
dc.identifier.affiliationsDepartment of Pharmacognosy, Goa College of Pharmacy, Panaji, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacognosy, Goa College of Pharmacy, Panaji, Indiaen_US
dc.identifier.affiliationsB N Degree College, Dandeli 581 325, India.en_US
dc.identifier.affiliationsDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, S S Nagar, Mysuru 570015, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, S S Nagar, Mysuru 570015, Indiaen_US
dc.identifier.citationHabbu Prasanna V., Miskin Narayan, Venkatrao H. Kulkarni, Bhat Pradeep, Joshi Arun, Bhandarkar Anant, Kulkarni Satish, Dixit Sheshagiri R., Vaijanathappa Jaishree. Isolation, characterization, and cytotoxic studies of secondary metabolites from the leaves of Bauhinia foveolata Dalzell: An endemic tree from the Western Ghats, India. Journal of Applied Pharmaceutical Science. 2020 Mar; 2020 Mar: 135-148en_US
dc.identifier.issn2231-3354
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/210718
dc.languageenen_US
dc.publisherOpen Science Publishers LLPen_US
dc.relation.issuenumber3en_US
dc.relation.volume10en_US
dc.source.urihttps://dx.doi.org//10.7324/JAPS.2020.103018en_US
dc.subjectBauhinia foveolataen_US
dc.subject13-Docosenamideen_US
dc.subjectflavonoidsen_US
dc.subjectcytotoxicityen_US
dc.titleIsolation, characterization, and cytotoxic studies of secondary metabolites from the leaves of Bauhinia foveolata Dalzell: An endemic tree from the Western Ghats, Indiaen_US
dc.typeJournal Articleen_US
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