Evaluation of alternative diagnostic techniques for diagnosis of cerebral malaria in a tertiary referral hospital in Bangladesh.

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dc.contributor.authorHossain, M Aen_US
dc.contributor.authorAfroj, Sen_US
dc.contributor.authorRahman, M Ren_US
dc.contributor.authorYunus, E Ben_US
dc.contributor.authorSamad, Ren_US
dc.contributor.authorAsna, Z Hen_US
dc.contributor.authorAkter, Sen_US
dc.contributor.authorFaiz, M Aen_US
dc.date.accessioned2008-07-16en_US
dc.date.accessioned2009-05-27T03:53:18Z
dc.date.available2008-07-16en_US
dc.date.available2009-05-27T03:53:18Z
dc.date.issued2008-07-16en_US
dc.descriptionMymensingh Medical Journal.en_US
dc.description.abstractFive alternative techniques for diagnosis of malaria were evaluated in 124 clinically diagnosed cerebral malaria cases admitted in a tertiary hospital in Bangladesh. Clinical diagnosis of cerebral malaria was done by WHO criteria. The tests were conventional routine malaria microscopy; prolonged microscopy; dipstick antigen capture assay (Para Sight TM-F test); pigments in peripheral leucocytes and routine microscopy repeated at 12 hours interval. First four tests were done at 0 hours of hospital admission and repeat routine microscopy was added at 12 hours interval. Diagnostic capability of the test was 64%, 65%, 69%, 27% and 63% respectively. None of the tests except pigments in peripheral leucocytes was superior at initial evaluation. Only the dipstick test added 5% more diagnostic possibility compared with routine microscopy as standard. Stratification of diagnostic capability in different ways improved diagnosis 15% and 11% in smear negative cases by dipstick and prolonged microscopy respectively. It was increased by 50% (5/10 patients) with dipstick test in the smear negative patients with history of anti-malarials prior to hospital admission.en_US
dc.description.affiliationBangladesh Institute of Tropical and Infectious Diseases, Chittagong, Bangladesh.en_US
dc.identifier.citationHossain MA, Afroj S, Rahman MR, Yunus EB, Samad R, Asna ZH, Akter S, Faiz MA. Evaluation of alternative diagnostic techniques for diagnosis of cerebral malaria in a tertiary referral hospital in Bangladesh. Mymensingh Medical Journal. 2008 Jul; 17(2): 180-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/1359
dc.language.isoengen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntigens, Protozoanen_US
dc.subject.meshBangladeshen_US
dc.subject.meshBrain Diseases --complicationsen_US
dc.subject.meshChilden_US
dc.subject.meshDNA, Protozoanen_US
dc.subject.meshDiagnostic Techniques and Procedures --instrumentationen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlasgow Coma Scaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMalaria, Cerebral --complicationsen_US
dc.subject.meshMaleen_US
dc.subject.meshMicroscopyen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshParasitic Sensitivity Testsen_US
dc.subject.meshPlasmodium falciparum --isolation & purificationen_US
dc.subject.meshReagent Kits, Diagnosticen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSensitivity and Specificityen_US
dc.titleEvaluation of alternative diagnostic techniques for diagnosis of cerebral malaria in a tertiary referral hospital in Bangladesh.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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