Is ulcer recurrence after simple closure of perforated duodenal ulcer predictable?

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dc.contributor.authorAnanthakrishnan, Nen_US
dc.contributor.authorAngami, Ken_US
dc.date.accessioned1993-07-01en_US
dc.date.accessioned2009-05-29T03:13:20Z
dc.date.available1993-07-01en_US
dc.date.available2009-05-29T03:13:20Z
dc.date.issued1993-07-01en_US
dc.description.abstractOBJECTIVE: To study whether factors such as age, duration of pre-perforation symptoms, size of perforation and operative evidence of chronicity could predict recurrence of ulcer after simple closure of perforated duodenal ulcers, thus enabling patients at high risk of recurrence to be subjected to definitive surgery instead of simple closure of perforation. DESIGN: Retrospective. One hundred and fifty-two patients who had undergone simple closure of duodenal ulcer perforation in the last 10 years were included in the study. SETTING: A postgraduate research and teaching institution. PATIENTS AND MEASUREMENTS: Patients were subjected to a personal interview and Visick grading of symptoms 1-10 years after simple closure of duodenal ulcer perforation. Ninety of them underwent esophagogastroduodenoscopic evaluation. RESULTS: Symptomatic ulcer recurrence rate was 23.1% by Visick grading and 42.2% on endoscopy. Ulcer symptom recurrence rate had no correlation with patient's age, duration of pre-perforation symptoms, or size of perforation, but correlated significantly with operative evidence of chronicity (p < 0.001). However, 7 of 35 symptomatic recurrences would have been missed by the use of this criterion alone. Endoscopic evidence of recurrence also correlated only with operative evidence of chronicity. False positives and false negatives with Visick grading showed that this symptomatic evaluation was unsatisfactory even for selecting patients for further endoscopic workup. CONCLUSION: Though not infallible, evidence of chronicity of ulcer at laparotomy may be a useful predictor of recurrence of ulcer after simple closure of perforated duodenal ulcer.en_US
dc.description.affiliationDepartment of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry.en_US
dc.identifier.citationAnanthakrishnan N, Angami K. Is ulcer recurrence after simple closure of perforated duodenal ulcer predictable? Indian Journal of Gastroenterology. 1993 Jul; 12(3): 80-2en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/65081
dc.language.isoengen_US
dc.source.urihttps://www.indianjgastro.comen_US
dc.subject.meshAdulten_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshDuodenal Ulcer --complicationsen_US
dc.subject.meshEndoscopy, Digestive Systemen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPeptic Ulcer Perforation --surgeryen_US
dc.subject.meshRecurrenceen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.titleIs ulcer recurrence after simple closure of perforated duodenal ulcer predictable?en_US
dc.typeJournal Articleen_US
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