A new occlusive patch test system comparable to IQ and Finn chambers.

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dc.contributor.authorMerchant, Shaziya Z Sajun
dc.contributor.authorVaidya, Ashlesha D
dc.contributor.authorSalvi, Anjali
dc.contributor.authorJoshi, Rajiv S
dc.contributor.authorMohile, Rashmikant B
dc.date.accessioned2015-01-08T09:39:01Z
dc.date.available2015-01-08T09:39:01Z
dc.date.issued2014-07
dc.description.abstractBackground: A good patch test system should have good adhesion and contact, and minimal leakage; Finn and IQ patch test system have these properties but are expensive. Aims: To develop a new cost‑effective occlusive patch test system that had good contact with the skin and was non‑irritant. Methods: The system (designated Chamber X) was fabricated using a semi‑permeable tape and a flexible virgin plastic chamber. Chamber X was developed by (i) selecting adhesive tape based on its non irritancy and adhesive potential (ii) testing plastic chamber material for its skin irritancy (iii) testing the assembled system against Finn, IQ and locally available chambers for irritancy, contact, leakage and occlusivity. Results: Chamber X showed better occlusion than IQ, Finn and locally available chambers and was comparable to, (P > 0.05) IQ and Finn in terms of irritancy, contact and leakage. Conclusions: The results demonstrate that the Chamber X offers a cost effective patch test system comparable to IQ and Finn chambers in terms of safety, adhesion, leakage and occlusivity.en_US
dc.identifier.citationMerchant Shaziya Z Sajun, Vaidya Ashlesha D, Salvi Anjali, Joshi Rajiv S, Mohile Rashmikant B. A new occlusive patch test system comparable to IQ and Finn chambers. Indian Journal of Dermatology, Venereology and Leprology. 2014 Jul-Aug; 80(4): 291-295.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/154839
dc.language.isoenen_US
dc.source.urihttps://www.ijdvl.com/article.asp?issn=0378-6323;year=2014;volume=80;issue=4;spage=291;epage=295;aulast=Sajunen_US
dc.subjectAllergy testingen_US
dc.subjectChamber Xen_US
dc.subjectclinical trialen_US
dc.subjectFinn chambersen_US
dc.subjecthuman patch testen_US
dc.subjectIQ chambersen_US
dc.subject.meshAllergens --administration & dosage
dc.subject.meshAllergens --metabolism
dc.subject.meshDermatitis, Allergic Contact --diagnosis
dc.subject.meshDermatitis, Allergic Contact --metabolism
dc.subject.meshEquipment Design --standards
dc.subject.meshEquipment Design --trends
dc.subject.meshHumans
dc.subject.meshIrritants --administration & dosage
dc.subject.meshIrritants --metabolism
dc.subject.meshPatch Tests --standards
dc.subject.meshPatch Tests --trends
dc.subject.meshSkin --metabolism
dc.titleA new occlusive patch test system comparable to IQ and Finn chambers.en_US
dc.typeArticleen_US
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