Presentation of a matrix-based method to calculate dose distribution in brachytherapy with photon-emitting sources

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dc.contributor.authorGhorbani, Mahdien_US
dc.contributor.authorMozaffari, Azamen_US
dc.contributor.authorAkbari-Lalimi, Hosseinen_US
dc.date.accessioned2020-11-18T10:07:29Z
dc.date.available2020-11-18T10:07:29Z
dc.date.issued2019-12
dc.description.abstractAim of Study: The report of the task group number 43(TG-43) of AAPM has been known as the most common method to obtain the dose distribution around brachytherapy sources. The error caused by independent obtaining and rounding and combinational error caused by algebraic operations of each TG-43 dosimetry parameters increase the total error in the calculation of the dose distribution around the brachytherapy sources. The aim of the present study is to present and evaluate a matrix-based approach for simplifying and reducing calculation errors. Materials and Methods: In this study, the simulation method with MCNPX code was used to obtain the dose distribution. Four sources were simulated, and the dose matrix around these sources was obtained. Finally, the dose distribution obtained from the matrix-based method was compared with the dose distribution obtained from the method of TG-43 report. Results: There is little difference between the values obtained from the two methods in some points. Absolute mean differences between the values obtained by these two methods were 1.4% for the 60Co, 3.52% for the 137Cs, 2.67% for the 192Ir, and 2.42% for the 103Pd sources. The advantage of the matrix-based method is its simple computing process and less computation time. Conclusion: Considering that the comparison of brachytherapy sources is not raised in calculations of treatment planning systems and also considering the more uncertainty in the calculation of the dose distribution in TG-43 method, it is recommended that dose distribution obtained from matrix-based method be used as input for treatment planning systems.en_US
dc.identifier.affiliationsDepartment of Medical Physics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iranen_US
dc.identifier.citationGhorbani Mahdi, Mozaffari Azam, Akbari-Lalimi Hossein. Presentation of a matrix-based method to calculate dose distribution in brachytherapy with photon-emitting sources. Journal of Cancer Research and Therapeutics. 2019 Oct; 15(5): 1245-1253en_US
dc.identifier.issn0973-1482
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/213517
dc.languageenen_US
dc.publisherWolters Kluwer India Pvt. Ltd.en_US
dc.relation.issuenumber5en_US
dc.relation.volume15en_US
dc.source.urihttps://dx.doi.org//10.4103/jcrt.JCRT_1274_16en_US
dc.subjectBrachytherapyen_US
dc.subjectdose distributionen_US
dc.subjectmatrix‑based approachen_US
dc.subjectMonte Carlo simulationen_US
dc.subjecttask group number 43 reportsen_US
dc.titlePresentation of a matrix-based method to calculate dose distribution in brachytherapy with photon-emitting sourcesen_US
dc.typeJournal Articleen_US
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