Efficacy of tyndalized Lactobacillus acidophilus in acute diarrhea.

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dc.contributor.authorKhanna, Vikranten_US
dc.contributor.authorAlam, Seemaen_US
dc.contributor.authorMalik, Ashrafen_US
dc.contributor.authorMalik, Abidaen_US
dc.date.accessioned2005-11-05en_US
dc.date.accessioned2009-05-30T10:07:00Z
dc.date.available2005-11-05en_US
dc.date.available2009-05-30T10:07:00Z
dc.date.issued2005-11-05en_US
dc.description.abstractOBJECTIVE: A double-blind randomized controlled-trial was done to evaluate the efficacy of tyndalized Lactobacillus acidophilus in acute diarrhea. METHODS: All children from 6 months to 12 years with acute diarrhea were included. Lactobacillus acidophilus/placebo was given to the children for 3 days with ORS and feeds. Intake-output was recorded 4 hourly. Of the 98 children, 48 received lactobacillus and 50 the placebo. RESULTS: ORS consumed, frequency of stools, duration of diarrhea, time for rehydration, hospital stay, weight gain and IVF needed were comparable in the two study groups. There were 4 treatment failures in the lactobacillus group and none in the placebo group (OR 0.92, 95%CI 0.84-0.99). In the rotaviral diarrhea and in those who had diarrhea of less then 60 hours the difference did not reach statistical significance. CONCLUSION: There is no significant benefit of tyndalized Lactobacillus acidophilus in acute diarrhea.en_US
dc.description.affiliationDepartment of Pediatrics, JN Medical College, Aligarh Muslim University, Aligarh, India.en_US
dc.identifier.citationKhanna V, Alam S, Malik A, Malik A. Efficacy of tyndalized Lactobacillus acidophilus in acute diarrhea. Indian Journal of Pediatrics. 2005 Nov; 72(11): 935-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/78313
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshDiarrhea --therapyen_US
dc.subject.meshDouble-Blind Methoden_US
dc.subject.meshFluid Therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshLactobacillus acidophilusen_US
dc.subject.meshProbiotics --therapeutic useen_US
dc.titleEfficacy of tyndalized Lactobacillus acidophilus in acute diarrhea.en_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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