Role of estradiol in the capacitation and acrosome reaction of hamster epididymal spermatozoa in the isolated uterus of mice incubated in vitro.

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dc.contributor.authorBathla, Hen_US
dc.contributor.authorGuraya, S Sen_US
dc.contributor.authorSangha, G Ken_US
dc.date.accessioned1999-04-12en_US
dc.date.accessioned2009-06-01T07:20:25Z
dc.date.available1999-04-12en_US
dc.date.available2009-06-01T07:20:25Z
dc.date.issued1999-04-12en_US
dc.description.abstractThe site of sperm capacitation, the agents and mechanisms causing capacitation and acrosome reaction (AR) in vivo are not well understood. The female reproductive tract has been reported to play a key role during capacitation and AR. Some experiments were carried out on the capacitation and AR of hamster epididymal spermatozoa in the estrogen and progesterone dominated uterus (estrous and diestrous respectively) albino mice, incubated in TALP without calcium and BSA. Also the effect of estradiol (200 micrograms/ml) supplemented to TALP, on capacitation and AR was examined. Capacitation and AR of hamster spermatozoa incubated in the isolated uterus of both estrous and diestrous mice were significantly (P < 0.05) higher in the presence of exogenous estradiol than that in its absence. Acrosome shedding occurred earlier i.e. at 3rd hour as compared to the in vitro studies where it occurred at 5th hour. The present study thus reveals that uterus of both estrogen and progesterone dominated mice play an important role in the induction of capacitation and AR. The addition of estradiol might have the influence on the synthesis of uterine proteins of mice which might be important for capacitation and AR.en_US
dc.description.affiliationDepartment of Zoology, Punjab Agricultural University, Ludhiana.en_US
dc.identifier.citationBathla H, Guraya SS, Sangha GK. Role of estradiol in the capacitation and acrosome reaction of hamster epididymal spermatozoa in the isolated uterus of mice incubated in vitro. Indian Journal of Physiology and Pharmacology. 1999 Apr; 43(2): 211-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/108080
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAcrosome Reaction --physiologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCalcium --physiologyen_US
dc.subject.meshCricetinaeen_US
dc.subject.meshEpididymis --cytologyen_US
dc.subject.meshEstradiol --physiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshMaleen_US
dc.subject.meshMiceen_US
dc.subject.meshProgesterone --physiologyen_US
dc.subject.meshSperm Capacitation --physiologyen_US
dc.subject.meshSpermatozoa --physiologyen_US
dc.subject.meshUterus --drug effectsen_US
dc.titleRole of estradiol in the capacitation and acrosome reaction of hamster epididymal spermatozoa in the isolated uterus of mice incubated in vitro.en_US
dc.typeIn Vitroen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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