Effect of adenosine and inosine on carbon tetrachloride-induced liver damage in rats.

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Date
1992-01-01
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Abstract
Liver damage induced in rats by carbon tetrachloride (CCL4) was obvious macroscopically as well as microscopically in stained sections. Levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and gamma glutamyl transpeptidase (gamma-GT) were also significantly raised. Adenosine and inosine effectively countered the damage when these were given before and during the period during which CCl4 produces the typical damage. The beneficial effect was seen in biochemical as well as pathological studies.
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Singh J, Garg KN, Yadav MS, Lal H. Effect of adenosine and inosine on carbon tetrachloride-induced liver damage in rats. Indian Journal of Physiology and Pharmacology. 1992 Jan; 36(1): 39-42
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https://imsear.searo.who.int/handle/123456789/108223
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Indian Journal of Physiology and Pharmacology