Coexistence of IgG4-related disease and tubercular lymphadenopathy in a rheumatoid arthritis patient

Simple item page
dc.contributor.authorChandra, SKen_US
dc.contributor.authorDastidar, AGen_US
dc.contributor.authorSinghal, Pen_US
dc.contributor.authorSengupta, Sen_US
dc.contributor.authorBandyopadhyay, S.en_US
dc.date.accessioned2024-12-02T12:03:59Z
dc.date.available2024-12-02T12:03:59Z
dc.date.issued2024-01
dc.description.abstractExtrapulmonary tuberculosis is a very common cause of generalised lymphadenopathy especially in tuberculosis endemic regions like India. A 33-year-old lady who had been diagnosed with rheumatoid arthritis 5 years back and had received treatment with biologicals including adalimumab presented with a 3 week history of persistent fever associated with significant weight loss and abdominal fullness. Investigations pointed towards a picture of tubercular aetiology although, a definite microbiological diagnosis was not possible at this stage. Patient also had an underlying subacute thyroiditis with diffusely increased uptake in Tc99 scan. Considering the background risk factor of use of biologicals and typical clinical presentation resembling tuberculosis, a decision to start antitubercular therapy was taken. The fever resolved but it recurred after 2 weeks and then after an extensive workup, the diagnosis of coexistent IgG4- related disease along with microbiological diagnosis of tuberculosis was established. This case highlights the importance of an active search for coexistent pathologies in cases of lymphadenopathy with insufficient response to standard therapy.en_US
dc.identifier.affiliationsDept. of General Medicine, Apollo Multispeciality Hospital, Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsDept. of General Medicine, Apollo Multispeciality Hospital, Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsDept. of General Medicine, Apollo Multispeciality Hospital, Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsDept. of General Medicine, Apollo Multispeciality Hospital, Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsDept. of General Medicine, Apollo Multispeciality Hospital, Kolkata, West Bengal, Indiaen_US
dc.identifier.citationChandra SK, Dastidar AG, Singhal P, Sengupta S, Bandyopadhyay S. . Coexistence of IgG4-related disease and tubercular lymphadenopathy in a rheumatoid arthritis patient. Journal of Applied Biology & Biotechnology. 2024 Jan; 11(1): 6-9en_US
dc.identifier.issn2319-1090
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/240874
dc.languageenen_US
dc.publisherIP Innovative Publication Pvt. Ltd.en_US
dc.relation.issuenumber1en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.18231/j.sajcrr.2024.002en_US
dc.subjectIgG4-related diseaseen_US
dc.subjectLymphadenopathyen_US
dc.subjectSubacute thyroiditisen_US
dc.subjectTuberculosisen_US
dc.subjectCastleman’s diseaseen_US
dc.titleCoexistence of IgG4-related disease and tubercular lymphadenopathy in a rheumatoid arthritis patienten_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
sajcrr2024v11n1p6.pdf
Size:
782.82 KB
Format:
Adobe Portable Document Format
Download
Collections
The Southeast Asian Journal of Case Report and Reviews