Heparin therapy in Russell's viper bite victims with disseminated intravascular coagulation: a controlled trial.

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dc.contributor.authorTin Na Swe,en_US
dc.contributor.authorMyint Lwin,en_US
dc.contributor.authorKhin Ei Han,en_US
dc.contributor.authorTin Tun,en_US
dc.contributor.authorTun, P een_US
dc.date.accessioned2009-05-27T16:58:04Z
dc.date.available2009-05-27T16:58:04Z
dc.date.issued1992-06-01en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractA controlled clinical trial of low dose heparin was carried out in confirmed cases of Russell's viper bite. Twenty patients with systemic envenoming were included in the study. They were randomized to receive low dose heparin in an initial dose of 50 units/kg body weight intravenously immediately after antivenom followed by a continuous infusion of 10 unit 3 kg/hour in isotonic saline for 24 hours, or antivenom alone. Response to treatment was assessed clinically as well as by serial measurements of coagulation factors and biochemical values. No significant difference was observed in the outcome among two groups, the recovery rate from the clotting defect being similar in both. The mean serum creatinine values of the two groups were also not statistically different. The results indicated that there is no beneficial effect of adding heparin to the standard treatment by antivenom.en_US
dc.description.affiliationClinical Research Unit for Snakebite, Department of Medical Research, Yangon, Myanmar.en_US
dc.identifier.citationTin Na Swe , Myint Lwin , Khin Ei Han , Tin Tun , Tun P. Heparin therapy in Russell's viper bite victims with disseminated intravascular coagulation: a controlled trial. The Southeast Asian Journal of Tropical Medicine and Public Health. 1992 Jun; 23(2): 282-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/36417
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAdulten_US
dc.subject.meshAntivenins --administration & dosageen_US
dc.subject.meshDisseminated Intravascular Coagulation --drug therapyen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshFactor X --immunologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeparin --administration & dosageen_US
dc.subject.meshHumansen_US
dc.subject.meshInfusions, Intravenousen_US
dc.subject.meshInjections, Intravenousen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSnake Bites --blooden_US
dc.subject.meshViper Venoms --adverse effectsen_US
dc.titleHeparin therapy in Russell's viper bite victims with disseminated intravascular coagulation: a controlled trial.en_US
dc.typeClinical Trialen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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