Pathogen burden & associated antibiogram of Pseudomonas spp. in a tertiary care hospital of India

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dc.contributor.authorKumari, Men_US
dc.contributor.authorKhurana, Sen_US
dc.contributor.authorBhardwaj, Nen_US
dc.contributor.authorMalhotra, Ren_US
dc.contributor.authorMathur, Pen_US
dc.date.accessioned2020-04-10T01:41:46Z
dc.date.available2020-04-10T01:41:46Z
dc.date.issued2019-02
dc.description.abstractAntimicrobial resistance particularly in Gram-negative bacilli is an increasing problem worldwide. Pseudomonas spp. is one the most common Gram-negative bacteria associated with nosocomial infections and therefore, its trend of antimicrobial resistance needs to be studied. The aim of this study was to evaluate the rate of antimicrobial resistance and changes in resistance pattern over a period of five years (2012-2016) in Pseudomonas spp. isolated from trauma patients attending a tertiary care hospital in north India. During the study, a total of 2444 Pseudomonas spp. were isolated from the various clinical sample. The most common species isolated was P. aeruginosa (2331, 95%). The highest level of resistance was observed against levofloxacin (1678, 69%) and the lowest level of resistance was observed against tobramycin (1254, 51%). Irrational and inappropriate use of antibiotics was found to be responsible for multidrug resistance in Pseudomonas spp. Hence, there is an urgent need to emphasize strict antibiotic policy to minimize the misuse of antimicrobials.en_US
dc.identifier.affiliationsDivision of Trauma Surgery & Critical Care, Jai Prakash Narayan Apex Trauma Centre, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Laboratory Medicine, Jai Prakash Narayan Apex Trauma Centre, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Orthopaedics, All India Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.citationKumari M, Khurana S, Bhardwaj N, Malhotra R, Mathur P. Pathogen burden & associated antibiogram of Pseudomonas spp. in a tertiary care hospital of India. Indian Journal of Medical Research. 2019 Feb; 149(2): 295-298en_US
dc.identifier.issn0971-5916
dc.identifier.issn0975-9174
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/195809
dc.languageenen_US
dc.publisherIndian Council of Medical Researchen_US
dc.relation.issuenumber2en_US
dc.relation.volume149en_US
dc.source.urihttps://dx.doi.org/10.4103/ijmr.IJMR_14_18en_US
dc.subjectAntimicrobialen_US
dc.subjectinfectionen_US
dc.subjectresistanceen_US
dc.subjectsurveillanceen_US
dc.subjectsusceptibilityen_US
dc.titlePathogen burden & associated antibiogram of Pseudomonas spp. in a tertiary care hospital of Indiaen_US
dc.typeJournal Articleen_US
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