A Comparative Study of Fluticasone Propionate, Mometasone Furoate, and Saline Nasal Spray in the Treatment of Children with Adenoid Hypertrophy

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dc.contributor.authorSingh, Gurbaxen_US
dc.contributor.authorJolly, Pushkalen_US
dc.contributor.authorPrinja, Sumiten_US
dc.contributor.authorBawa, A. G. Sen_US
dc.contributor.authorVignesh, A. Ken_US
dc.date.accessioned2023-07-14T07:59:04Z
dc.date.available2023-07-14T07:59:04Z
dc.date.issued2023-06
dc.description.abstractIntroduction:Adenoidectomy is currently considered the treatment of choice for relief of the nasal airway obstruction due to adenoid hypertrophy. Evidence suggests that topical nasal steroid sprays can cause a reduction in adenoid size. We aim to compare the effectiveness of fluticasone propionate, mometasone furoate (MF) and saline nasal sprays in relieving the signs and symptoms of adenoid hypertrophy and in reducing the size of the adenoids. MaterialsandMethods: We conducted a randomized comparative study on 60 patients divided into three groups A, B, C (20 each). Group A patients treated with fluticasone propionate nasal spray (400 μg/day), Group B patients treated with MF nasal spray (100 μg/day), and Group C patients treated with saline spray (0.65% w/v in purified water which is made isotonic and buffered). Treatment was given up to 12 weeks with follow‑up at 4, 8, and 12 weeks and at each follow‑up visit assessment was done. Final data were analyzed using SPSS software version 21 and numerical variables associated with different groups were analyzed and analysis of variance test was used. Results: Diagnostic nasal endoscopy and X‑ray grades at day 1 among the study groups were not statistically significant, whereas, at 12 weeks results among fluticasone and mometasone groups were significantly better (P < 0.001) as compared to the saline group. There was a significant improvement in the symptoms under all the categories with the use of fluticasone and mometasone. Conclusion: In our study, both fluticasone propionate and MF were able to effectively reduce symptoms and signs of adenoid hypertrophy as well as help in reducing the size of the enlarged adenoid. Both these drugs were well tolerated by the patientsen_US
dc.identifier.affiliationsDepartment of ENT, GGS Medical College and Hospital, Faridkot, Punjab, Indiaen_US
dc.identifier.citationSingh Gurbax, Jolly Pushkal, Prinja Sumit, Bawa A. G. S, Vignesh A. K. A Comparative Study of Fluticasone Propionate, Mometasone Furoate, and Saline Nasal Spray in the Treatment of Children with Adenoid Hypertrophy. Acta Medica International. 2023 Jun; 10(1): 59-64en_US
dc.identifier.issn2349-0896
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/219169
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume10en_US
dc.source.urihttps://doi.org/10.4103/amit.amit_38_23en_US
dc.subjectAdenoid hypertrophyen_US
dc.subjectadenoidectomyen_US
dc.subjectfluticasone propionateen_US
dc.subjectmometasone furoateen_US
dc.titleA Comparative Study of Fluticasone Propionate, Mometasone Furoate, and Saline Nasal Spray in the Treatment of Children with Adenoid Hypertrophyen_US
dc.typeJournal Articleen_US
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