Detection of early xerophthalmia by impression cytology and rose Bengal staining--a comparative study.
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1992-04-01
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Abstract
Twenty two cases were studied for early detection of Xerophthalmia by impression cytology and Rose Bengal staining. Patients were below 6 years of age and admitted in the paediatric ward of Dhaka Medical College Hospital. Assessment were done by conjunctival impression cytology and staining with 1% Rose Bengal dye. Estimation of serum retinol level was done by HPLC to correlate conjunctival findings with biochemical status. The mean age of the subjects were 3.15 +/- 1.75. Rose Bengal staining was positive in 40% cases and impression cytology was in 60% cases. The mean serum retinol level of the diseased children were 10.5 +/- 3. ug/dl. The sensitivity of Rose Bengal staining was 53.3% and that of impression cytology was 80% in detecting vitamin A deficiency when compared with serum retinol level. The specificity of Rose Bengal staining was 40% and that of impression cytology was 100%. Sensitivity of impression cytology was 100% in patient with retinol level 10 ug/dl.
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Bangladesh Medical Research Council Bulletin.
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Khan AN, Huda S, Ahmed AN, Hossain T, Sultana N, Ali SM. Detection of early xerophthalmia by impression cytology and rose Bengal staining--a comparative study. Bangladesh Medical Research Council Bulletin. 1992 Apr; 18(1): 1-11