Is Liver Frailty and functional capacity associated with severity of liver disease in patients awaiting Liver Transplantation? - A prospective Observational Study

Simple item page
dc.contributor.authorVakani, Nirali S.en_US
dc.contributor.authorShah, Harda H.en_US
dc.contributor.authorModi, Pranjalen_US
dc.contributor.authorSutariya, Vaibhaven_US
dc.contributor.authorTiwari, Bharaten_US
dc.date.accessioned2024-09-24T08:26:56Z
dc.date.available2024-09-24T08:26:56Z
dc.date.issued2023-04
dc.description.abstractBackground: Liver is a major metabolic organ, interfering with the function of all organs and systems. So, the patients with severe liver disease may display wide manifestations of metabolic disorders, loss of muscle mass and function. Combination of these factors leads to decreased exercise tolerance and physical inactivity and it may be exaggerated with increasing severity of liver disease. The functional capacity could be severely affected due to multiple physiological derangements in these population. Hence, a liver transplant is the only cure for end stage liver disease. Currently only few literature are available that evaluated and described the status of frailty and functional capacity in these population. So we have tried to evaluate the same in Indian Population. Methodology: After ethical commttee approval and written inform consent, 85 cirrhotic atients who fulfilled the Inclusion and Exclusion criteria were included in the study. Disease specific history, Severity of Liver disease, Physical evalution of frailty via Hand grip strength, Balance and time taken to do 5 chair stands , subjective functional capacity evaluation was done through Duke activity status Index (DASI). Result: In 85 patients, the average Hand grip strength was 23.70 ± 10.60kg in males and 15.02± 5.08kg in females , average value of timed chair stands (TCS) was 18.18± 6.60 in males and 14.18± 8.65 in females , average balance score was 28.00 ±4.99 in males and 29.33± 2.58 in females and the average value of MELDNa was 22.2± 6.9. Conclusion: When compared with normal Indian standard Liver cirrhotic patient, form of frailty and reduced functional capacity non predominant. That stressed emphasis on rehabilitation and nutritional counselling during waiting period for Transplantation.en_US
dc.identifier.affiliationsLecturer, IKDRC-ITS College of Physiotherapy, Civil Hospital Campus, Asarwa, Ahmedabad,Gujarat, Indiaen_US
dc.identifier.affiliationsSenior Lecturer PT, PhD, IKDRC-ITS College of Physiotherapy, Civil Hospital Campus, Asarwa,Ahmedabad, Gujarat, Indiaen_US
dc.identifier.affiliationsHead of Department of Urology and Abdominal Organ Transplantation and Vice-chancellor, GujaratUniversity of Transplantation Sciences, Civil hospital Campus, Asarwa, Ahmedabad, Indiaen_US
dc.identifier.affiliationsProfessor, Department of Abdominal Organ Transplantation Surgery, IKDRC-ITS Hospital, CivilHospital Campus, Asarwa, Ahmedabad, Gujarat, Indiaen_US
dc.identifier.affiliationsI/C Principal and Senior Lecturer IKDRC-ITS College of Physiotherapy, Civil Hospital Campus,Asarwa, Ahmedabad, Gujarat, India.en_US
dc.identifier.citationVakani Nirali S., Shah Harda H., Modi Pranjal, Sutariya Vaibhav, Tiwari Bharat. Is Liver Frailty and functional capacity associated with severity of liver disease in patients awaiting Liver Transplantation? - A prospective Observational Study. International Journal of Physiotherapy and Research. 2023 Mar; 11(2): 4476-4482en_US
dc.identifier.issn2321-1822
dc.identifier.issn2321-8975
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/231335
dc.languageenen_US
dc.publisherPorticoen_US
dc.relation.issuenumber2en_US
dc.relation.volume11en_US
dc.source.urihttps://dx.doi.org/10.16965/ijpr.2023.111en_US
dc.subjectMetabolic disordersen_US
dc.subjectNon-predominanten_US
dc.subjectCounselling.en_US
dc.titleIs Liver Frailty and functional capacity associated with severity of liver disease in patients awaiting Liver Transplantation? - A prospective Observational Studyen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ijpr2023v11n2p4476.pdf
Size:
1.09 MB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Physiotherapy and Research