The efficacy of Thai capsaicin in management of overactive bladder and hypersensitive bladder.

dc.contributor.authorSoontrapa, Suchaien_US
dc.contributor.authorRuksakul, Wirojen_US
dc.contributor.authorNonthasood, Bunjerden_US
dc.contributor.authorTappayuthpijarn, Pimolvanen_US
dc.date.accessioned2009-05-27T17:55:28Z
dc.date.available2009-05-27T17:55:28Z
dc.date.issued2003-09-03en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractThis paper has been generated to provide information on the effectiveness of capsaicin treatment among patients with overactive or hypersensitive bladder. The evaluation process required approximately 14 (overactive bladder) and 11 (hypersensitive bladder and primary detrusor instability) participants who received capsaicin intravesically. The solution consisted of capsaicin (concentration = 1 mM/L) diluted in 30 per cent ethanol solution 100 ml. All participants went through at least 1 urodynamic test 1 month before and after receiving capsaicin intravesical instillation. The capsaicin treatment for overactive and hypersensitive bladders was very effective. On the average, (overactive bladder) participants' voiding needs decreased from 16.5 +/- 4.8 times/day to 8.6 +/- 2.5 times/day, leakage from 9.7 +/- 8.1 times/day to 2.4 +/- 4.3 times/day, bladder capacity from 160.1 +/- 123.3 ml to 236.9 +/- 146.1 ml, and detrusor contraction from 71.1 +/- 29.2 cm/H2O to 57.3 +/- 27.2 cm/H2O. On average, (hypersensitive bladder and primary detrusor instability) participants' voiding needs decreased from (Day time) 19.45 +/- 17.99 times to 12.00 +/- 8.91 times/day, (Night time) 7.09 +/- 6.03 times to 4.09 +/- 3.8 times, bladder capacity from 197.40 +/- 156.06 ml to 323.45 +/- 129.46 ml, and detrusor contraction from 32.64 +/- 22.77 cm/H2O to 36.64 +/- 19.22 cm/H2O. Capsaicin efficiency was rated very high for both overactive and hypersensitive bladder and primary detrusor instability. In Thailand, it has been possible to produce capsaicin using local chili supplies, thus the price of the drug itself is very economical. When considering the efficiency and the inexpensive cost of capsaicin, this treatment would be another great alternative for overactive and hypersensitive bladder cure.en_US
dc.description.affiliationDepartment of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.en_US
dc.identifier.citationSoontrapa S, Ruksakul W, Nonthasood B, Tappayuthpijarn P. The efficacy of Thai capsaicin in management of overactive bladder and hypersensitive bladder. Journal of the Medical Association of Thailand. 2003 Sep; 86(9): 861-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/38086
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdministration, Intravesicalen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCapsaicin --administration & dosageen_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshUrination Disorders --physiopathologyen_US
dc.subject.meshUrodynamicsen_US
dc.titleThe efficacy of Thai capsaicin in management of overactive bladder and hypersensitive bladder.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description: