A Child with Serious Chikungunya Virus (CHIKV) Infection Requiring Intensive Care, After an Outbreak.
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Date
2010-11
Journal Title
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Volume Title
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Abstract
A 5 1/2-yr-old boy presented with high grade
fever for 4 days, and cervical adenitis, body ache,
arthralgia, followed by sudden onset of breathlessness. He
had clinical, electrocardiographic and echo evidence of
myocarditis and congestive cardiac failure. An enzymelinked
immunosorbent assay (MAC-IgM ELISA) with
serum collected 5 days after disease onset showed IgM
antibodies to CHIKV. He was managed conservatively and
started showing symptomatic improvement by 3 days. At
discharge, a repeat Echocardiogram (a week later) showed
normal left ventricular (LV) function with mild Mitral
regurgitation. On follow up, after 2 months, child remains
asymptomatic. Other common aetiological agents were
screened for and found negative. This may indicate a
probable cardiac tropism for the virus.
Description
Keywords
Cardiac dysfunction, Critically ill child, Viral infections
Citation
Menon P Ramesh, Krishnan C, Sankar Jayaram, Gopinathan K M, Mohan Girija. A Child with Serious Chikungunya Virus (CHIKV) Infection Requiring Intensive Care, After an Outbreak. Indian Journal of Pediatrics. 2010 Nov ; 77 (11): 1326-1328.