Serum Interleukin-6 Levels in Children with Febrile Seizures
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Date
2018-05
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Academy of Pediatrics
Abstract
Objectives: To compare levels of Interleukin-6 (IL-6) in children with febrile seizures andfebrile controls. Methods: Study conducted in a tertiary-care hospital in Northern India fromNovember 2013 to April 2015, enrolling 160 children (80 each with febrile seizures and febrilecontrols), aged 6 – 60 months. Serum IL-6 estimated by ELISA method. Iron study done asper standard technique. All the cases of febrile seizure were followed up at 1 week, 3 monthsand 6 months for recurrence of seizures. Results: The mean serum IL-6 levels in childrenwith febrile seizures was 62.0 (63.9) pg/mL and febrile controls was 86.9 (70.6) pg/mL(P=0.025). Conclusion: Serum IL-6 levels were significantly lower in children with febrileseizures as compared to febrile controls.
Description
Keywords
Cytokines, Inflammation, Iron profile
Citation
Gupta Surbhi, Aggarwal Anju, MMA Faridi, Rai Gargi, Das Shukla, Kotru Mrinalini. Serum Interleukin-6 Levels in Children with Febrile Seizures. Indian Pediatrics. 2018 May; 55(5): 411-413