Association Between Nutrition Status and Cognitive Impairment Among COPD Patients and age Matched Healthy Controls

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dc.contributor.authorRandeep, Mannen_US
dc.contributor.authorDogra, Archanaen_US
dc.contributor.authorSarkar, Malayen_US
dc.contributor.authorPadam, Anitaen_US
dc.date.accessioned2019-12-06T09:21:08Z
dc.date.available2019-12-06T09:21:08Z
dc.date.issued2018-09
dc.description.abstractBackground:Nutritional abnormalities & Cognitive decline are frequent systemic manifestations associated with COPD. The study aimed to investigate and compare the cognitive & nutritive parameters in COPD with age matched healthy controls, and to find association between cognitive impairment & nutrition parameters. Methods: 100 subjects were recruited, and divided into two groups. Group I consisted of fifty consecutive physician diagnosed COPD patients & Group II included fifty healthy volunteers respectively. The spirometric parameters recorded were FEV1 (Liters), FVC (liters), FEV1/FVC ratio(% predicted),FEF 25%75%(liters/sec). Anthropometric measurements included Body Weight, Height and BMI measurements. Nutritional status was assessed using mini nutritional questionnaire (MNA). Body composition was assessed by four-frequency bioelectric impedance analysis (BODY STAT, QUADSCAN, USA). The following parameters were calculated: FFM, FFMI & FMI. The exercise capacity was assessed by the six minute walking distance test (6MWD). MMSE (mini mental state examination) and MOCA (montreal cognitive assessment) were used for cognitive function. All the recordings were compared within and between groups and correlation was also computed between MMSE, MOCA and MNA score. Results were analyzed using SPSS,version 16 & Pearson correlation coefficient. Results: We found out that COPD patients showed decline in all the parameters as compared to healthy controls. And, great strength of association was found between MNA & MOCA in COPD patients. Conclusion: Thus our study indicates that COPD patients have age independent loss of muscle mass as well as cognition, and loss of cognition is associated with decline in nutritional parameters or vice versa.en_US
dc.identifier.affiliationsAssistant professor, Department of Physiology, Pt. JLNGMC, Chamba.en_US
dc.identifier.affiliationsAssistant professor, Department of Physiology, GMC, Nahan.en_US
dc.identifier.affiliationsProfessor & Head Department of Pulmonary medicine IGMC, Shimla.en_US
dc.identifier.affiliationsProfessor & Head Department of Physiologyen_US
dc.identifier.citationRandeep Mann, Dogra Archana, Sarkar Malay, Padam Anita. Association Between Nutrition Status and Cognitive Impairment Among COPD Patients and age Matched Healthy Controls. Annals of International medical and Dental Research. 2018 Sep; 4(5): 8-12en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/188278
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber5en_US
dc.relation.volume4en_US
dc.source.urihttps://doi.org/10.21276/aimdr.2018.4.5.PH3en_US
dc.titleAssociation Between Nutrition Status and Cognitive Impairment Among COPD Patients and age Matched Healthy Controlsen_US
dc.typeJournal Articleen_US
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