Measles related complications and the role of vitamin A supplementation.

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dc.contributor.authorMishra, Ashoken_US
dc.contributor.authorMishra, Subodhen_US
dc.contributor.authorJain, Pankajen_US
dc.contributor.authorBhadoriya, Rahul Singhen_US
dc.contributor.authorMishra, Rakeshen_US
dc.contributor.authorLahariya, Chandrakanten_US
dc.date.accessioned2008-09-06en_US
dc.date.accessioned2009-05-30T16:00:21Z
dc.date.available2008-09-06en_US
dc.date.available2009-05-30T16:00:21Z
dc.date.issued2008-09-06en_US
dc.description.abstractOBJECTIVE: Measles is associated with high rate of complications and contributes to a major proportion of childhood morbidity and mortality. The role of vit A supplementation (VAS) in the case management of measles and prevention of complications is partially understood and not sufficiently supported by epidemiological data. This paper analyses the possible role of vit A supplementation in prevention of measles related complications and associated fatality. METHODS: A cross sectional study was carried out during an outbreak of measles in Shivpuri, India. A total population of 193,000 was covered by house to house visit and, the caregivers of total 1204 measles cases, including 214 cases with complications, were interviewed using a semi structured interview schedule. The analysis of data was done using Epi Info. RESULTS: The attack rate of 6.7% and rate of complications at 17.8% were found in this investigation. The coverage with routine measles vaccine and the vit A supplementation was 18.3% and 28.9% respectively. The management of measles cases was poor with only 15.8% cases receiving therapeutic doses of vit A. Both complications and case fatality rate was higher amongst children who had not received vit A supplementation in previous 6 months (p<0.05). Measles vaccine also found to have preventive effect on development of complications (p<0.05). CONCLUSION: Routine vit A supplementation and measles vaccination reduce the chances of complications amongst cases of measles. The role of VAS becomes more important when the case management is poor. While, measles is frequently associated with complications in the Indian setting, there is a need of enhancing the efforts to improve the delivery of vit A supplementation and measles vaccine to the children in rural areas.en_US
dc.description.affiliationDepartment of Community Medicine, Gajara Raja Medical College and Associated JA Group of Hospitals, Gwalior, 474009, India.en_US
dc.identifier.citationMishra A, Mishra S, Jain P, Bhadoriya RS, Mishra R, Lahariya C. Measles related complications and the role of vitamin A supplementation. Indian Journal of Pediatrics. 2008 Sep; 75(9): 887-90en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/84157
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshCross-Sectional Studiesen_US
dc.subject.meshDisease Outbreaks --prevention & controlen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshMeasles --complicationsen_US
dc.subject.meshMeasles Vaccine --administration & dosageen_US
dc.subject.meshQuestionnairesen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshVitamin A --administration & dosageen_US
dc.subject.meshVitamin A Deficiency --epidemiologyen_US
dc.titleMeasles related complications and the role of vitamin A supplementation.en_US
dc.typeJournal Articleen_US
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