Complement-dependent lymphocytotoxicity crossmatch in deceased donor renal transplant: A single institutional experience.

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dc.contributor.authorDeepa, R
dc.contributor.authorBalapriya, P
dc.contributor.authorVenkatesh, K G
dc.contributor.authorSabeetha, T
dc.contributor.authorSasikala, J
dc.contributor.authorJayalakshmi, G
dc.date.accessioned2012-12-14T10:18:19Z
dc.date.available2012-12-14T10:18:19Z
dc.date.issued2011-10
dc.description.abstractComplement-dependent lymphocytotoxicity crossmatches (n=217) between 47 deceased donors and 150 potential renal recipients were retrospectively studied. A negative cross match was reported in 48 (22.1%), doubtful positive in 126 (58.1%), weakly positive in 32 (14.7%) and positive in 11 (5.1%). No autoantibodies were detected. Renal transplantation was performed in 35.5% of the potential recipients. There was no incidence of hyperacute rejection. The graft survival rate was 88% at 15 months of follow up. The study concludes that a negative pretransplant lympocytotoxicity crossmatch using the basic National Institute of Health technique eliminates hyperacute rejection, but carries drawbacks, which require modification and supplementation with more sensitive and specific assays.en_US
dc.identifier.citationDeepa R, Balapriya P, Venkatesh K G, Sabeetha T, Sasikala J, Jayalakshmi G. Complement-dependent lymphocytotoxicity crossmatch in deceased donor renal transplant: A single institutional experience. Indian Journal of Medical Microbiology. 2011 Oct-Dec; 29(4): 414-417.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/143867
dc.language.isoenen_US
dc.source.urihttps://www.ijmm.org/article.asp?issn=0255-0857;year=2011;volume=29;issue=4;spage=414;epage=417;aulast=Deepaen_US
dc.subjectComplement dependant lymphocytotoxicityen_US
dc.subjectcross matchen_US
dc.subjectdeceased donor renal transplanten_US
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshChild
dc.subject.meshChild, Preschool
dc.subject.meshComplement System Proteins --immunology
dc.subject.meshCytotoxicity Tests, Immunologic --methods
dc.subject.meshFemale
dc.subject.meshGraft Rejection --immunology
dc.subject.meshGraft Survival --immunology
dc.subject.meshHistocompatibility Testing --methods
dc.subject.meshHumans
dc.subject.meshKidney Transplantation --immunology
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshRetrospective Studies
dc.subject.meshTreatment Outcome
dc.subject.meshYoung Adult
dc.titleComplement-dependent lymphocytotoxicity crossmatch in deceased donor renal transplant: A single institutional experience.en_US
dc.typeArticleen_US
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