An attempt to reduce the loss of pain and touch sensations in leprosy patients.
dc.contributor.author | Jain, G L | en_US |
dc.contributor.author | Pasricha, J S | en_US |
dc.contributor.author | Guha, S K | en_US |
dc.date.accessioned | 1986-04-01 | en_US |
dc.date.accessioned | 2009-05-28T10:32:11Z | |
dc.date.available | 1986-04-01 | en_US |
dc.date.available | 2009-05-28T10:32:11Z | |
dc.date.issued | 1986-04-01 | en_US |
dc.description.abstract | An attempt was made to improve the perception of pain and touch sensations at the leprosy lesions. The loss of pain and touch sensations in a lesion was graded using Pain/Touch-Sensation-Testing-and-Grading devices. Application of a solution containing 1 mg of histamine per ml of DMSO, at the affected area decreased the grades of the loss of pain sensation in 11 (31.4%) patients and of touch sensation in 8 (22.8%) patients, out of the 35 patients tested, indicating an improvement in the perception at the lesion. This effect, however, did not persist even for 5 minutes. A higher concentration (2 mg/ml) of histamine produced reduction in the sensory loss in a larger percentage (47% for pain and 35.3% for touch) of patients, though the duration of this effect was still not prolonged. | en_US |
dc.identifier.citation | Jain GL, Pasricha JS, Guha SK. An attempt to reduce the loss of pain and touch sensations in leprosy patients. Indian Journal of Leprosy. 1986 Apr-Jun; 58(2): 225-32 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/55472 | |
dc.language.iso | eng | en_US |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Aged, 80 and over | en_US |
dc.subject.mesh | Child | en_US |
dc.subject.mesh | Dimethyl Sulfoxide --pharmacology | en_US |
dc.subject.mesh | Drug Combinations | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Histamine --analogs & derivatives | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Leprosy --physiopathology | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Nervous System Diseases --physiopathology | en_US |
dc.subject.mesh | Pain --physiopathology | en_US |
dc.subject.mesh | Pain Measurement | en_US |
dc.subject.mesh | Sensory Thresholds --drug effects | en_US |
dc.subject.mesh | Temperature Sense --drug effects | en_US |
dc.subject.mesh | Touch | en_US |
dc.title | An attempt to reduce the loss of pain and touch sensations in leprosy patients. | en_US |
dc.type | Journal Article | en_US |
dc.type | Research Support, Non-U.S. Gov't | en_US |
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