Need of the hour: pharmacovigilance study of SGLT-2 inhibitors

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dc.contributor.authorPradhan, Sapnaen_US
dc.contributor.authorA., Tejusen_US
dc.contributor.authorKoley, Mrinalinien_US
dc.contributor.authorMathur, A. G.en_US
dc.date.accessioned2020-11-18T09:58:06Z
dc.date.available2020-11-18T09:58:06Z
dc.date.issued2019-04
dc.description.abstractBackground: Diabetes mellitus represents a global pandemic. Various pharmacotherapy and non-pharmacotherapy measures are advocated for its control. The latest in the pharmacotherapy are Sodium Glucose Transporter -2 (SGLT-2) inhibitors, widely used. Many studies suggest adverse effects related to SGLT-2 inhibitors, evidence still not conclusive and few data from India. Hence this study was planned.Methods: Cross-sectional study over a period of 02 months, recorded demographic details and history of various adverse drug reactions reported with the use of SGLT-2 inhibitors.Results: Majority of the study participants were females (58%) and belonged to the age group of 40-70 yrs. Urinary tract infections (UTI) and genital infections was more seen in the users of dapagliflozin, followed by empagliflozin and canagliflozin.Conclusions: SGLT-2 Inhibitors offer a unique therapeutic approach to the management of Diabetes Mellitus. Further evaluation of the safety profile and the risk-benefit analysis is the need of the hour.en_US
dc.identifier.affiliationsDepartment of Pharmacology, Army College of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.citationPradhan Sapna, A. Tejus, Koley Mrinalini, Mathur A. G.. Need of the hour: pharmacovigilance study of SGLT-2 inhibitors. International Journal of Research in Medical Sciences. 2019 Apr; 7(4): 1093-1097en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/211282
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber4en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20191305en_US
dc.subjectDiabetes mellitusen_US
dc.subjectGenital infectionsen_US
dc.subjectPharmacovigilanceen_US
dc.subjectSafety profileen_US
dc.subjectSGLT-2 Inhibitorsen_US
dc.subjectUTIen_US
dc.titleNeed of the hour: pharmacovigilance study of SGLT-2 inhibitorsen_US
dc.typeJournal Articleen_US
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