Oral valganciclovir in human immunodeficiency virus-positive patients suffering from cytomegalovirus retinitis at a tertiary care hospital in North India

Simple item page
dc.contributor.authorMarkan, Ashishen_US
dc.contributor.authorGupta, Nikitaen_US
dc.contributor.authorDogra, Mohiten_US
dc.contributor.authorSharma, Amanen_US
dc.contributor.authorSingh, Ramandeepen_US
dc.date.accessioned2023-08-25T06:33:43Z
dc.date.available2023-08-25T06:33:43Z
dc.date.issued2022-07
dc.description.abstractPurpose: To study clinical efficacy of valganciclovir in cytomegalovirus retinitis (CMVR) in human immunodeficiency virus (HIV)?positive?positive patients in a tertiary care clinic in a developing nation. Methods: In a retrospective study, systemic and ocular records of HIV patients suffering from CMVR and treated with valganciclovir, were analyzed. Primary outcome measures were involvement of the other eye, incidence of retinal detachment, systemic involvement, and mortality encountered. Secondary outcome measures included change in BCVA. Results: Out of nine patients who were included, two patients developed CMVR in the other eye and only one patient (11.11%) developed retinal detachment during the course of the study. No patient developed any systemic manifestations or had mortality during the course of the study. The change in BCVA was not statistically significant. Conclusion: Use of oral valganciclovir showed good outcome and was found to be a better alternative compared to the use of intravitreal ganciclovir in the literature. Introduction of valganciclovir at an affordable price in developing nations can decrease disease burdenen_US
dc.identifier.affiliationsAdvanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, Indiaen_US
dc.identifier.affiliationsDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, Indiaen_US
dc.identifier.citationMarkan Ashish, Gupta Nikita, Dogra Mohit, Sharma Aman, Singh Ramandeep. Oral valganciclovir in human immunodeficiency virus-positive patients suffering from cytomegalovirus retinitis at a tertiary care hospital in North India. Indian Journal of Ophthalmology. 2022 Jul; 70(7): 2472-2475en_US
dc.identifier.issn1998-3689
dc.identifier.issn0301-4738
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/224415
dc.languageenen_US
dc.publisherAll India Ophthalmological Societyen_US
dc.relation.issuenumber7en_US
dc.relation.volume70en_US
dc.source.urihttps://doi.org/10.4103/ijo.IJO_2787_21en_US
dc.subjectAIDSen_US
dc.subjectCMV retinitisen_US
dc.subjectdeveloping nationen_US
dc.subjectHIVen_US
dc.subjectsystemic therapyen_US
dc.subjectvalgancicloviren_US
dc.titleOral valganciclovir in human immunodeficiency virus-positive patients suffering from cytomegalovirus retinitis at a tertiary care hospital in North Indiaen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
IJO2022v70n7p2472.pdf
Size:
1.61 MB
Format:
Adobe Portable Document Format
Download
Collections
Indian Journal of Ophthalmology