Anticoagulant and antibacterial activities of polysaccharides of red algae Corallina collected from Lebanese coast.

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dc.contributor.authorSebaaly, Carine
dc.contributor.authorKassem, Sahar
dc.contributor.authorGrishina, Elena
dc.contributor.authorKanaan, Hussein
dc.contributor.authorSweidan, Alaa
dc.contributor.authorChmit, M Said
dc.contributor.authorKanaan, Hussein M
dc.date.accessioned2014-06-17T11:52:45Z
dc.date.available2014-06-17T11:52:45Z
dc.date.issued2014-04
dc.description.abstractIn this work, we studied another species of red algae, Corallina, growing on the Lebanese coast of Batroun. The analysis of trace elements showed that Corallina was rich in K, Ca, Mg, Na, Si, Sr, P and Fe. Corallina was composed of 70.81% of saturated fatty acids, 25.54% of monounsaturated fatty acids and 3.65% of polyunsaturated fatty acids with palmitic acid as the main component. Moreover, the total yield of sulfated galactans and carrageenan was 2.5% and 10%, respectively. Both extracts exhibited anticoagulant effect but sulfated galactans were less potent than carrageenan. Sulfated galactans possessed inhibitory activity as well as bactericidal activity against all Gram-positive strains tested (Enterococcus faecalis ATCC 29212 and Staphylococcus epidermidis CIP 444). But, carrageenan was only able to inhibit the growth of S. epidermidis with a minimal inhibitory concentration (MIC) of 0.325 mg/mL. Furthermore, infrared spectroscopy (IR) revealed that the isolated carrageenan was of Lambda-type. Corallina could therefore be considered as a potential source of bioactive molecules that may be useful for the development of new pharmaceutical agents.en_US
dc.identifier.citationSebaaly Carine, Kassem Sahar, Grishina Elena, Kanaan Hussein, Sweidan Alaa, Chmit M Said, Kanaan Hussein M. Anticoagulant and antibacterial activities of polysaccharides of red algae Corallina collected from Lebanese coast. Journal of Applied Pharmaceutical Science. 2014 Apr; 4(4): 30-37.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/152121
dc.language.isoenen_US
dc.source.urihttps://www.japsonline.com/counter.php?aid=1223en_US
dc.subjectRed algae Corallinaen_US
dc.subjectsulfated galactansen_US
dc.subjectcarrageenanen_US
dc.subjectantibacterialen_US
dc.subjectanticoagulanten_US
dc.titleAnticoagulant and antibacterial activities of polysaccharides of red algae Corallina collected from Lebanese coast.en_US
dc.typeArticleen_US
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