A simple screening test for the detection of heterozygous beta thalassemia.
dc.contributor.author | Thool, A A | en_US |
dc.contributor.author | Walde, M S | en_US |
dc.contributor.author | Shrikhande, A V | en_US |
dc.contributor.author | Talib, V H | en_US |
dc.date.accessioned | 1998-10-29 | en_US |
dc.date.accessioned | 2009-05-29T13:36:47Z | |
dc.date.available | 1998-10-29 | en_US |
dc.date.available | 2009-05-29T13:36:47Z | |
dc.date.issued | 1998-10-29 | en_US |
dc.description.abstract | Beta-Thalassemia is prevalent in a high frequency of 5-15% in selected geographical areas and ethnic communities. There is need to screen large populations for the heterozygotes of beta-Thalassemia. We have evaluated NESTROFT (Naked eye single tube red cell osmotic fragility test) with 0.36% buffered saline in this study. Of the population screened, 42 cases were positive with NESTROFT, of which 40 were positive with the confirmatory test for beta-Thalassemia. This implies a positive predictive value and specificity of 100%, negative predictive value of 83.3% and sensitivity of 95.2%. | en_US |
dc.description.affiliation | Department of Laboratory Medicine, Safdarjung Hospital, New Delhi. | en_US |
dc.identifier.citation | Thool AA, Walde MS, Shrikhande AV, Talib VH. A simple screening test for the detection of heterozygous beta thalassemia. Indian Journal of Pathology & Microbiology. 1998 Oct; 41(4): 423-6 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/75835 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://www.ijpmonline.org | en_US |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Child | en_US |
dc.subject.mesh | Child, Preschool | en_US |
dc.subject.mesh | Erythrocytes --metabolism | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Heterozygote Detection --methods | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Infant | en_US |
dc.subject.mesh | Longitudinal Studies | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Sensitivity and Specificity | en_US |
dc.subject.mesh | beta-Thalassemia --diagnosis | en_US |
dc.title | A simple screening test for the detection of heterozygous beta thalassemia. | en_US |
dc.type | Journal Article | en_US |
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