A simple screening test for the detection of heterozygous beta thalassemia.

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dc.contributor.authorThool, A Aen_US
dc.contributor.authorWalde, M Sen_US
dc.contributor.authorShrikhande, A Ven_US
dc.contributor.authorTalib, V Hen_US
dc.date.accessioned1998-10-29en_US
dc.date.accessioned2009-05-29T13:36:47Z
dc.date.available1998-10-29en_US
dc.date.available2009-05-29T13:36:47Z
dc.date.issued1998-10-29en_US
dc.description.abstractBeta-Thalassemia is prevalent in a high frequency of 5-15% in selected geographical areas and ethnic communities. There is need to screen large populations for the heterozygotes of beta-Thalassemia. We have evaluated NESTROFT (Naked eye single tube red cell osmotic fragility test) with 0.36% buffered saline in this study. Of the population screened, 42 cases were positive with NESTROFT, of which 40 were positive with the confirmatory test for beta-Thalassemia. This implies a positive predictive value and specificity of 100%, negative predictive value of 83.3% and sensitivity of 95.2%.en_US
dc.description.affiliationDepartment of Laboratory Medicine, Safdarjung Hospital, New Delhi.en_US
dc.identifier.citationThool AA, Walde MS, Shrikhande AV, Talib VH. A simple screening test for the detection of heterozygous beta thalassemia. Indian Journal of Pathology & Microbiology. 1998 Oct; 41(4): 423-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/75835
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshErythrocytes --metabolismen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeterozygote Detection --methodsen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshLongitudinal Studiesen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshbeta-Thalassemia --diagnosisen_US
dc.titleA simple screening test for the detection of heterozygous beta thalassemia.en_US
dc.typeJournal Articleen_US
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