A histopathological study of hearts and spleens of hamsters (Mesocricetus auratus) infected with Leptospira interrogans, serovar pyrogenes.

Simple item page
dc.contributor.authorMuensoongnoen, Jittimaen_US
dc.contributor.authorPhulsuksombati, Duangpornen_US
dc.contributor.authorParichatikanond, Paisalen_US
dc.contributor.authorSangjan, Noppadonen_US
dc.contributor.authorPilakasiri, Chaiyaphruken_US
dc.contributor.authorSripaoraya, Kesornen_US
dc.contributor.authorRoongruangchai, Jantimaen_US
dc.contributor.authorKoedpuech, Kasemen_US
dc.contributor.authorPilakasiri, Kajeeen_US
dc.date.accessioned2009-05-27T15:22:33Z
dc.date.available2009-05-27T15:22:33Z
dc.date.issued2006-07-24en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractThe effects of Leptospira interrogans on the heart and spleen of hamsters were studied histopathologically. Infected hamsters were sacrificed at 1 hour, 6 hours and on days 1, 2, 3, 4, 5 and 6 after inoculation with Leptospira interrogans serovar pyrogenes. The heart and spleen of each of the sacrificed animals were removed and processed for routine conventional light microscopy. Infected hearts showed degenerative change of the cardiac muscle cells composed of cellular swelling, condensation of chromatin granules, pyknotic nuclei and acidophilic cytoplasm. Congestion of the cardiac blood vessels and hemorrhagic areas were found. Necrosis of the cardiac muscle cells was surrounded by numerous inflammatory cells. In the spleen, cellular necrosis was found scattered throughout the splenic cord. The splenic sinusoids were dilated and congested with many hemorrhagic areas. Inflammatory cell infiltration was also noted in the splenic parenchyma and the splenic sinusoids.en_US
dc.description.affiliationDepartment of Anatomy, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.en_US
dc.identifier.citationMuensoongnoen J, Phulsuksombati D, Parichatikanond P, Sangjan N, Pilakasiri C, Sripaoraya K, Roongruangchai J, Koedpuech K, Pilakasiri K. A histopathological study of hearts and spleens of hamsters (Mesocricetus auratus) infected with Leptospira interrogans, serovar pyrogenes. The Southeast Asian Journal of Tropical Medicine and Public Health. 2006 Jul; 37(4): 720-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/32628
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/2006_37_4/17-3736.pdfen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCricetinaeen_US
dc.subject.meshLeptospira interrogansen_US
dc.subject.meshLeptospirosis --pathologyen_US
dc.subject.meshMyocardium --pathologyen_US
dc.subject.meshNecrosis --pathologyen_US
dc.subject.meshRodent Diseases --parasitologyen_US
dc.subject.meshSpleen --pathologyen_US
dc.subject.meshTime Factorsen_US
dc.titleA histopathological study of hearts and spleens of hamsters (Mesocricetus auratus) infected with Leptospira interrogans, serovar pyrogenes.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
720.pdf
Size:
247.02 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Southeast Asian Journal of Tropical Medicine and Public Health