Pattern of Alcohol Consumption in Patients of Alcoholic Liver Disease in India

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dc.contributor.authorGawande, Atulen_US
dc.contributor.authorMaharshi, Sudhiren_US
dc.contributor.authorWanjari, Shashanken_US
dc.contributor.authorGupta, Gaurav Kumaren_US
dc.contributor.authorNijhawan, Sandeepen_US
dc.contributor.authorSharma, Shyam Sunderen_US
dc.date.accessioned2023-07-21T11:38:52Z
dc.date.available2023-07-21T11:38:52Z
dc.date.issued2021-06
dc.description.abstractBackground: Alcohol-related chronic liver disease (ALD) and its complications are major causes of morbidity and mortality. Predisposing factors for ALD include the amount, type, duration of alcohol consumption, patient’s genetic predisposition, race, sex, and other comorbid conditions. Aims: To study the dose, duration, and type of alcohol consumption in ALD and the effect of these parameters on severity and outcome Methods: This was a prospective study conducted at the Department of Gastroenterology, SMS hospital, Jaipur, between December 2017 to December 2018. All patients with alcoholic liver disease admitted in the department were consecutively enrolled. Data relating to dose, duration, type, alcohol intake pattern, biochemical, ultrasonographic, and clinical parameters were analysed. Results: One hundred ten patients (age 43.5±9.9, all-male) were studied. Mean alcohol consumption was 130.47±35.37gm/day. Sixty-three (57.3%) patients consumed <120gm, 25(22.7%) between 120-239gm, while 22(20%) patients consumed =240gm of alcohol per day. The mean duration of alcohol consumption was 15.89±6.57 years. Fifty-nine (53.63%) patients consumed country-made spirit, 25 (22.72%) branded spirit, 23 (20.91%) mixed or variable type, while three (2.73%) patients consumed only wine. The occurrence of hepatic encephalopathy (HE) was significantly associated with dose (p <0.001) and type (p <0.001) of alcohol consumption. MELD Na score significantly correlated (r=0.48, p <0.001) with dose of alcohol. Conclusion: Our study found a dose-dependent relationship of alcohol intake with hepatic encephalopathy and MELD-Na score. The incidence of ALD did not change with the type of alcohol consumed. Low lymphocyte counts were significantly associated with dose and duration of alcohol intake.en_US
dc.identifier.affiliationsDepartment of Gastroenterology,SMS Medical College and Hospitals, Jaipur, India.en_US
dc.identifier.citationGawande Atul, Maharshi Sudhir, Wanjari Shashank, Gupta Gaurav Kumar, Nijhawan Sandeep, Sharma Shyam Sunder. Pattern of Alcohol Consumption in Patients of Alcoholic Liver Disease in India. Tropical Gastroenterology. 2021 Jun; 42(2): 84-91en_US
dc.identifier.issn0250-636X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/221044
dc.languageenen_US
dc.publisherAll India Institute of Medical Sciencesen_US
dc.relation.issuenumber2en_US
dc.relation.volume42en_US
dc.source.urihttps://dx.doi.org/10.7869/tg.629en_US
dc.subjectAlcoholic liver diseasesen_US
dc.subjectAlcoholen_US
dc.subjectIndia.en_US
dc.titlePattern of Alcohol Consumption in Patients of Alcoholic Liver Disease in Indiaen_US
dc.typeJournal Articleen_US
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