Cellular DNA contact and its correlation with histopathological prognostic parameters in carcinoma of the breast.

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dc.contributor.authorChaturvedi, Sen_US
dc.contributor.authorSingh, Sen_US
dc.contributor.authorKhanna, H Den_US
dc.contributor.authorKhanna, Sen_US
dc.contributor.authorKhanna, Ren_US
dc.date.accessioned1998-07-07en_US
dc.date.accessioned2009-05-29T10:58:15Z
dc.date.available1998-07-07en_US
dc.date.available2009-05-29T10:58:15Z
dc.date.issued1998-07-07en_US
dc.description.abstractPresent study has given an insight in to the value of the DNA in relation to other morphometrics. Breast cancer shows variability in clinical course in the same clinical stage. Cellular DNA content is an important prognostic parameter. Tumour tissue DNA content is correlated with known histopathological prognostic feature assessing its significance as prognostic parameter in 25 cases of carcinoma breast. The findings showed that cellular DNA content ranged between 1.5-5.08 ug/mg in cancer breast tissue with an average of 2.54 ug/mg as compared to an average of 1.34 ug/mg in normal breast tissue. The DNA content was higher in combined pattern, in poorly differentiated duct carcinoma and in patients with positive lymph node metastasis. No consistent relationship could be seen between cellular DNA and desmoplasia and lymphoreticular response in and around tumour.en_US
dc.description.affiliationDepartment of Pathology, Banaras Hindu University, Varanasi.en_US
dc.identifier.citationChaturvedi S, Singh S, Khanna HD, Khanna S, Khanna R. Cellular DNA contact and its correlation with histopathological prognostic parameters in carcinoma of the breast. Indian Journal of Pathology & Microbiology. 1998 Jul; 41(3): 337-42en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/73009
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshBreast Neoplasms --chemistryen_US
dc.subject.meshCarcinoma --chemistryen_US
dc.subject.meshDNA, Neoplasm --analysisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshPrognosisen_US
dc.titleCellular DNA contact and its correlation with histopathological prognostic parameters in carcinoma of the breast.en_US
dc.typeJournal Articleen_US
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