Studies on the stability of DMR hepatitis B vaccine
No Thumbnail Available
Date
1998-08-01
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The stability of the DMR hepatitis B vaccine at 4C and room temperature has been followed over a period of one year by monitoring its physical, chemical and biological characteristics bimonthly starting from February 1996. The pH and protein content of the vaccine did not change for both storage conditions throughout the study. The vaccines were found to be sterile and free from pyrogens and passed the general safety test on mice. The HBsAg titer started to decline after eight months of storage at 4C and after 10 days of storage at room temperature. However, the HBsAg adsorption rate to the adjuvant remained over 95 per cent for both storage conditions.
Description
Keywords
Citation
Khin Khin Aye, Cho Cho Lwin, Aye Kyaw, Khin Pyone Kyi, Maung Maung Khin, Than Swe. Studies on the stability of DMR hepatitis B vaccine. Myanmar Health Sciences Research Journal. 1998; 10(2): 61-63