Epitope specific monoclonal antibodies from heterologous antigen for immunodiagnosis of filariasis.

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dc.contributor.authorDhas, K Pen_US
dc.contributor.authorRaj, R Ken_US
dc.date.accessioned1995-05-01en_US
dc.date.accessioned2009-05-27T07:05:57Z
dc.date.available1995-05-01en_US
dc.date.available2009-05-27T07:05:57Z
dc.date.issued1995-05-01en_US
dc.description.abstractThe excretory secretory (ES) antigens produced from Setaria digitata were studied by PAGE and Western blot and compared with human filarial systems. Monoclonal antibodies (K3AE7 and K3BD5) developed against the ES antigen were evaluated by ELISA for the diagnosis of human filariasis. Cent per cent positive reaction was found with the circulating filarial antigen (CFA) of microfilaria carriers, occult and symptomatic patients and clear negative reaction with both the endemic and nonendemic controls. The clones offer promise for the development of highly sensitive diagnostic reagents for the detection of filariasis.en_US
dc.description.affiliationDepartment of Biochemistry, University of Kerala, Thiruvanathapuram.en_US
dc.identifier.citationDhas KP, Raj RK. Epitope specific monoclonal antibodies from heterologous antigen for immunodiagnosis of filariasis. Indian Journal of Medical Research. 1995 May; 101(): 183-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/19292
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntibodies, Monoclonalen_US
dc.subject.meshAntibody Specificityen_US
dc.subject.meshAntigens, Helminthen_US
dc.subject.meshEnzyme-Linked Immunosorbent Assayen_US
dc.subject.meshEpitopesen_US
dc.subject.meshFemaleen_US
dc.subject.meshFilariasis --diagnosisen_US
dc.subject.meshHumansen_US
dc.titleEpitope specific monoclonal antibodies from heterologous antigen for immunodiagnosis of filariasis.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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