Effectiveness of pulse oximetry screening for congenital heart disease in asymptomatic new-borns.

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dc.contributor.authorLanker, Audil Mohmad
dc.contributor.authorChowdhary, Javed
dc.contributor.authorJeelani, Nasir
dc.contributor.authorJeelani, Shazia
dc.contributor.authorHassan, Ashfaq Ul
dc.contributor.authorWani, Nasir-ud-din
dc.date.accessioned2015-11-09T09:50:30Z
dc.date.available2015-11-09T09:50:30Z
dc.date.issued2014-07
dc.description.abstractBackground: Congenital Cardio-Vascular Malformations (CCVMs) are relatively common with a prevalence of 5-10 in every 1000 live births. CCVM represents a new-born condition that would be ideally suited to a screening program if simple and reliable methods were available. Pulse oximetry has been proposed as a screening method for the detection of congenital heart defects. Methods: Hospital based prospective non-randomized study conducted over a period of one year at the department of pediatrics in G.B. Panth hospital (Neonatology) and L.D. hospital (Neonatology). A total of 1200 asymptomatic new-borns attending G.B. Panth, neonatology/L.D. neonatology were screened with pulse oximetry. Oximetric screening for CCVM was performed by obtaining a single determination of postductal saturation at >24 hours. All new-borns underwent additional evaluation by echocardiography. Results: Out of 1200 newborns screened three had postductal saturation ≤95%. Echocardiography revealed TGA (transposition of great vessels) in one; TA (truncus arteriosus) in other and third one had structurally normal heart on echocardiography. There was one false negative screen (found in the inpatient records of G.B. Panth hospital). The sensitivity, specificity, positive predictive value and negative predictive value of pulse oximetry in screening for CCVM in asymptomatic new-borns was found to be 66.67%, 99.9%, 66.67% and 99.9% respectively. Conclusion: This screening test is simple, non-invasive and inexpensive. The sensitivity, specificity, and predictive value in this population were satisfactory, indicating that screening should be applied to larger populations, particularly in developing countries where lower rates of detection result in increased CCVM prevalence in asymptomatic new-borns.en_US
dc.identifier.citationLanker Audil Mohmad, Chowdhary Javed, Jeelani Nasir, Jeelani Shazia, Hassan Ashfaq Ul, Wani Nasir-ud-din. Effectiveness of pulse oximetry screening for congenital heart disease in asymptomatic new-borns. International Journal of Research in Medical Sciences. 2014 Jul-Sept; 2(3): 1112-1116.en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/165369
dc.language.isoenen_US
dc.source.urihttps://www.msjonline.org/?mno=164100en_US
dc.subjectPulseen_US
dc.subjectCongenitalen_US
dc.subjectOxygenen_US
dc.subjectVascularen_US
dc.subjectMalformationen_US
dc.titleEffectiveness of pulse oximetry screening for congenital heart disease in asymptomatic new-borns.en_US
dc.typeArticleen_US
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