Serum alpha-1-antitrypsin in ischemia and rheumatic heart diseases.

Simple item page
dc.contributor.authorSomayajulu, G Len_US
dc.contributor.authorReddy, P Pen_US
dc.date.accessioned1996-10-01en_US
dc.date.accessioned2009-05-29T11:56:46Z
dc.date.available1996-10-01en_US
dc.date.available2009-05-29T11:56:46Z
dc.date.issued1996-10-01en_US
dc.description.abstractTissue damage, inflammation and necrosis are hallmarks of myocardial infarction. In the present study significant elevations of serum alpha-1-antitrypsin were noted in coronary artery disease and angina cases. Interestingly chronic rheumatic heart disease which is also characterized by tissue injury. Inflammation revealed normal levels of serum alpha-1-antitrypsin. The level in chronic rheumatic heart disease was 3.37 +/- 0.57 mumol/mt/ml (control level was 3.37 +/- 0.54 mumol/mt/ml). The corollary of these observations is that in heart diseases acute phase response in terms of enhanced levels of alpha-1-antitrypsin differ depending on the causative factors. Except chronic rheumatic heart disease, in all other stressful states studied there is (to a certain degree) an altered systemic homeostasis and haemostasis. On the other hand chronic rheumatic heart disease encompass certain amount of acute phase status in terms of tissue damage and inflammation does exist unaccompanied by altered systemic homeostasis and haemostasis. However, bacteriological etiologies predominate the triggered immune responses. It is hypothesised that serum alpha-1-antitrypsin enhancement will not occur even though acute phase state exists if specific immune responses are also a part of the disease manifestation.en_US
dc.description.affiliationDepartment of Pathology, Osmania Medical College, Hyderabad.en_US
dc.identifier.citationSomayajulu GL, Reddy PP. Serum alpha-1-antitrypsin in ischemia and rheumatic heart diseases. Indian Journal of Pathology & Microbiology. 1996 Oct; 39(4): 271-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/74064
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBlood Chemical Analysisen_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMyocardial Ischemia --metabolismen_US
dc.subject.meshRheumatic Heart Disease --metabolismen_US
dc.subject.meshalpha 1-Antitrypsin --analysisen_US
dc.titleSerum alpha-1-antitrypsin in ischemia and rheumatic heart diseases.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Pathology & Microbiology